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CD8 抗体 (PE,Cy5)

CD8 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal OX-8 PE,Cy5
产品编号 ABIN133193
发货至: 中国
  • 抗原 See all CD8 抗体
    CD8
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    大鼠
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    小鼠
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    单克隆
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    This CD8 antibody is conjugated to PE,Cy5
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Rat CD8a
    纯化方法
    Ion exchange
    克隆位点
    OX-8
    亚型
    IgG1
    Top Product
    Discover our top product CD8 Primary Antibody
  • 限制
    仅限研究用
  • 浓度
    0.2 mg/ml
    储存条件
    4 °C
  • 抗原
    CD8
    别名
    CD8 (CD8 产品)
    别名
    CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, CD8a molecule antibody, CD8A antibody
    背景
    Anti-rat CD8a monoclonal antibody recognizes a determinant on the majority of thymocytes (90-95%), a subset of peripheral T cells, the majority of NK cells, and the granular intraepithelial leukocytes in the small intestine. (1,2,3,4.) The antigen recognized is a complex of surface glycoproteins of Mr 34,000, 39,000 and 76,000 Da and is the rat homologue of the human CD8 and the mouse Ly-2,3 antigen. (5,8) ABIN133193labels all peripheral T cells that are unlabelled by the ABIN000000 (W3/25) monoclonal antibody. It labels a T-cell subset which mediates the suppression of antibody formation (1) and the cytotoxic cell precursor. (2) ABIN133193and ABIN000000 can be used together to fractionate T cells by sorting in FACS or by rosette depletion (1,2) or can be used together to study subsets of T cells in the rat which mediate lethal graft vs. host disease. (7) This antibody is one of the 3 monoclonal antibodies which labels T lymphocyte populations in the rat, these being ABIN000000 (W3/13) which labels all T cells, as well as ABIN000000 (W3/25) and CL004TC(MRC 0X-8) which label non-overlapping T cell populations. These monoclonal antibodies used in concert are being employed extensively to investigate cellular aspects of the immune response in rats and prove to be useful as markers for functionally distinct subpopulations of lymphocytes.
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