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CD84 抗体 (FITC)

Name: CD84 抗体 (FITC)
Brand: antibodies-online
SKU: ABIN1302945
Availability: OutOfStock

CD84 适用: 人 FACS 宿主: 小鼠 Monoclonal CD84-1-21 FITC

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD84 (CD84. (CD84 抗体 (FITC))

FACS

Flow cytometry analysis (surface staining) of CD84 in human peripheral blood with anti-CD84 (CD84. (CD84 抗体 (FITC))

FACS

Separation of human CD177 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD84 (CD84. (CD84 抗体 (FITC))

FACS

3 images

(4 references)

产品编号 ABIN1302945

发货至: 中国

Datasheet as PDF

抗原 See all CD84 抗体

CD84
适用
64

23

16

1
人
宿主
51

29

1
小鼠
Compatible Secondaries
克隆类型
51

29

1
单克隆
标记
33

7

6

5

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD84 antibody is conjugated to FITC
应用范围
46

42

25

10

9

5

4

2

2

2
Flow Cytometry (FACS)

特异性

The mouse monoclonal antibody CD84.1.21 recognizes an extracellular epitope of CD84, a single chain cell surface glycoprotein of 64-82 kDa, predominantly expressed B cells, monocytes, platelets and some T cells.

交叉反应（详细）

Human

纯化方法

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

CD84-transfected 300.19 cell line

克隆位点

CD84-1-21

亚型

IgG2a kappa

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CD84 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5B9E10 unconjugated

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CD84 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5D12H10 unconjugated

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CD84 适用: 小鼠, 大鼠 FACS, WB, ELISA 宿主: 兔 Polyclonal unconjugated

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CD84 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G10 unconjugated

anti-CD84 (CD84) antibody
CD84 适用: 人 FACS, IP, Func 宿主: 小鼠 Monoclonal CD84-1-21 unconjugated

anti-CD84 (CD84) antibody
CD84 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal CD84-1-21 unconjugated

anti-CD84 (CD84) (AA 22-225) antibody
CD84 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-CD84 (CD84) (AA 1-328) antibody
CD84 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-CD84 (CD84) antibody
CD84 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 152-1D5 unconjugated

应用备注

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

说明

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

限制

仅限研究用
溶解方式

No reconstitution is necessary.

缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.
Avoid prolonged exposure to light.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

Morra, Lu, Poy, Martin, Sayos, Calpe, Gullo, Howie, Rietdijk, Thompson, Coyle, Denny, Yaffe, Engel, Eck, Terhorst: "Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells." in: The EMBO journal, Vol. 20, Issue 21, pp. 5840-52, (2001) (PubMed).

Martin, Romero, de la Fuente, Tovar, Zapater, Esplugues, Pizcueta, Bosch, Engel: "CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 7, pp. 3668-76, (2001) (PubMed).

Sayós, Martín, Chen, Simarro, Howie, Morra, Engel, Terhorst: "Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP." in: Blood, Vol. 97, Issue 12, pp. 3867-74, (2001) (PubMed).
抗原

CD84

别名

CD84 (CD84 产品)

别名

RGD1564553 antibody, A130013D22Rik antibody, CDw84 antibody, SLAMF5 antibody, LY9B antibody, hCD84 antibody, mCD84 antibody, CD84 molecule antibody, CD84 antigen antibody, Cd84 antibody, CD84 antibody

背景

CD84 Molecule,CD84 is a highly glycosylated homophilic receptor of SLAM family. It is expressed on platelets and various types of leukocytes, especially following their activation. Ligation of CD84 leads to its phosphorylation on tyrosine residues within the cytoplasmic tail. These docking sites are recognized by downstream signaling molecules, such as phosphatase SHP-2 and adaptor protein SAP/SH2D1A. The function of CD84 has not been fully elucidated yet. Although predominantly activating receptor, its modulating activity was also demonstrated.,LY9B, SLAMF5

基因ID

8832

UniProt

Q9UIB8