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DC-SIGN/CD209 抗体

CD209 适用: 人 FACS, IHC, ICC 宿主: 小鼠 Monoclonal UW60-1 unconjugated
产品编号 ABIN1302458
发货至: 中国
  • 抗原 See all DC-SIGN/CD209 (CD209) 抗体
    DC-SIGN/CD209 (CD209) (CD209)
    适用
    • 99
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    宿主
    • 75
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    小鼠
    克隆类型
    • 74
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    单克隆
    标记
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    This DC-SIGN/CD209 antibody is un-conjugated
    应用范围
    • 72
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    特异性
    The mouse monoclonal antibody UW60.1 recognizes an extracellular epitope of human CD209 (DC-SIGN), a 44 kDa transmembrane receptor, expressed on the surface of dendritic cells and macrophages.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    CD209-His-tagged fusion protein
    克隆位点
    UW60-1
    亚型
    IgG2a
    Top Product
    Discover our top product CD209 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Ryan, Marshall, Magaletti, Floyd, Draves, Olson, Clark: "Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 5638-48, (2002) (PubMed).

  • 抗原
    DC-SIGN/CD209 (CD209) (CD209)
    别名
    CD209 (CD209 产品)
    别名
    CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, cd209 antibody, CLEC4M antibody, si:ch211-224h1.3 antibody, CD209 antibody, CIRE antibody, Dcsign antibody, SIGN-R1 antibody, SIGNR5 antibody, Cd209 antibody, CD209 molecule antibody, CD209a antigen antibody, CD209 antigen-like protein D antibody, CD209c molecule antibody, CD209 antigen antibody, CD209 antibody, cd209 antibody, Cd209a antibody, LOC100529184 antibody, Cd209c antibody, LOC100460708 antibody, LOC105484282 antibody
    背景
    CD209 Molecule,CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).,CLEC4L, DC-SIGN1, CDSIGN
    基因ID
    30835
    UniProt
    Q9NNX6
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