CCDC98 抗体 (AA 1-313)
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- 抗原 See all CCDC98 (FAM175A) 抗体
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
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抗原表位
- AA 1-313
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CCDC98 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody ABRA1-01 recognizes human ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions.
- 交叉反应 （详细）
- Human, Other not tested
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
- 克隆位点
- ABRA1-01
- 亚型
- IgG
- Top Product
- Discover our top product FAM175A Primary Antibody
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anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 51-150) antibody
FAM175A 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 1-313) antibodyFAM175A 适用: 人 WB, IP, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal ABRA1-01 unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 350-400) antibodyFAM175A 适用: 人 WB, IP, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (N-Term) antibodyFAM175A 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Flow cytometry: Recommended dilution: 1-2 μg/mL. Intracellular staining.
Western blotting: Reducing conditions. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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- 抗原
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
- 别名
- ABRA1 (FAM175A 产品)
- 别名
- CCDC98 antibody, abra1 antibody, ccdc98 antibody, fam175a antibody, ABRA1 antibody, 3830405G04Rik antibody, 5630400M01Rik antibody, AI506069 antibody, AL024423 antibody, AV118690 antibody, Ccdc98 antibody, RGD1305287 antibody, zgc:103522 antibody, abraxas 1, BRCA1 A complex subunit antibody, Coiled-coil domain-containing protein 98 antibody, BRCA1 A complex subunit antibody, family with sequence similarity 175 member A antibody, abraxas 2a, BRISC complex subunit antibody, abraxas 1, BRCA1 A complex subunit S homeolog antibody, ABRAXAS1 antibody, abraxas1 antibody, Abraxas1 antibody, FAM175A antibody, abraxas2a antibody, abraxas1.S antibody
- 背景
- Abraxas 1, BRCA1 A complex subunit,ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.,ABRA1, Abraxas 1, CCDC98, FAM175A
- 基因ID
- 84142
- UniProt
- Q6UWZ7
- 途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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