PPP1R13L 抗体 (Isoform 1)
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- 抗原 See all PPP1R13L 抗体
- PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))
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抗原表位
- AA 780-797, Isoform 1
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPP1R13L antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 780-797 of human iASPP protein.
- 亚型
- IgG
- Top Product
- Discover our top product PPP1R13L Primary Antibody
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect bands approximately 100 kDa and 50 kDa in size corresponding to isoforms 1 and 2 respectively of iASPP protein by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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ASPP--Apoptotic specific regulator of p53." in: Biochimica et biophysica acta, Vol. 1756, Issue 1, pp. 77-80, (2005) (PubMed).
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ASPP--Apoptotic specific regulator of p53." in: Biochimica et biophysica acta, Vol. 1756, Issue 1, pp. 77-80, (2005) (PubMed).
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- 抗原
- PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))
- Abstract
- PPP1R13L 产品
- 别名
- AV260376 antibody, IASPP antibody, Nkip1 antibody, wa3 antibody, zgc:113058 antibody, NKIP1 antibody, RAI antibody, RAI4 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 13 like antibody, protein phosphatase 1, regulatory subunit 13 like antibody, protein phosphatase 1 regulatory subunit 13 like antibody, protein phosphatase 1 regulatory subunit 13 like L homeolog antibody, Ppp1r13l antibody, ppp1r13l antibody, PPP1R13L antibody, ppp1r13l.L antibody
- 背景
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ASPP proteins (ASPP1, ASPP2 and iASPP) represent a new family of p53 binding proteins. ASPP1 and ASPP2 bind and enhance p53-mediated apoptosis. In contrast, the third member, iASPP, functionally inactivates p53. iASPP (also called protein phosphatase 1 regulatory (inhibitor) subunit 13 like protein, Inhibitor of ASPP protein, Protein iASPP, PPP1R13B-like protein and NFkB-interacting protein 1) plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. iASPP blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1.
Synonyms: inhibitor of apoptosis stimulating protein of p53 antibody, Inhibitor of ASPP protein antibody, NFkB interacting protein 1 antibody, NKIP1 antibody, PPP1R13B-like protein antibody - 基因ID
- 10848, 63003907
- UniProt
- Q8WUF5
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