(6 references)-
- 抗原 See all CTCFL 抗体
- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
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抗原表位
- AA 9-26
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CTCFL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- Chimpanzee
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 9-26 of human BORIS protein.
- 亚型
- IgG
- Top Product
- Discover our top product CTCFL Primary Antibody
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anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-270) antibody
CTCFL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) antibodyCTCFL 适用: 人 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 617-650) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal RB54304 unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-636) antibodyCTCFL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) antibodyCTCFL 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 211-260) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 36-85) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-270) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) antibodyCTCFL 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a predominant band approximately 75 kDa in size corresponding to BORIS by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.28 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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: "BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells." in: Cell death discovery, Vol. 6, pp. 1, (2020) (PubMed).
: "A cell cycle role for the epigenetic factor CTCF-L/BORIS." in: PLoS ONE, Vol. 7, Issue 6, pp. e39371, (2012) (PubMed).
: "Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 9, pp. 1841-50, (2012) (PubMed).
: "CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer." in: Molecular cancer research : MCR, Vol. 9, Issue 2, pp. 225-33, (2011) (PubMed).
: "BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas." in: PLoS ONE, Vol. 5, Issue 3, pp. e9738, (2010) (PubMed).
: "Selective apoptosis of breast cancer cells by siRNA targeting of BORIS." in: Biochemical and biophysical research communications, Vol. 370, Issue 1, pp. 109-12, (2008) (PubMed).
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: "BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells." in: Cell death discovery, Vol. 6, pp. 1, (2020) (PubMed).
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- 抗原
- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
- 别名
- BORIS (CTCFL 产品)
- 别名
- BORIS antibody, CT27 antibody, CTCF-T antibody, HMGB1L1 antibody, dJ579F20.2 antibody, CTCFL antibody, Boris antibody, OTTMUSG00000016680 antibody, CCCTC-binding factor like antibody, CCCTC-binding factor (zinc finger protein)-like antibody, CTCFL antibody, Ctcfl antibody
- 背景
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This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. BORIS (Brother of the Regulator of Imprinted Sites) also known as CCCTC-binding factor-like protein, is normally only expressed in the testis and expressed in a mutually exclusive manner with CTCF during male germ cell development. However, previous studies have shown that BORIS is abnormally activated in a wide range of human cancers. Expression of BORIS in normally BORIS-negative cells promotes cell growth that may lead to transformation. BORIS maps to the cancer-associated amplification region thought to contain an oncogene or dominant-immortalizing gene. BORIS is a candidate protein for the epigenetic reprogramming factor acting in the male germ line. BORIS is found in both the nucleus and cytoplasm.
Synonyms: Brother of the regulator of imprinted sites antibody, CCCTC binding factor (zinc finger protein) like antibody, CCCTC-binding factor antibody, CTCF paralog antibody, CTCF T antibody - 基因ID
- 140690, 20805280
- UniProt
- Q8NI51
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