HDAC1 抗体 (AA 466-482)
(3 references)-
- 抗原 See all HDAC1 抗体
- HDAC1 (Histone Deacetylase 1 (HDAC1))
-
抗原表位
- AA 466-482
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HDAC1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- Anti-HDAC-1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 466-482 of Human HDAC-1.
- 亚型
- IgG
- Top Product
- Discover our top product HDAC1 Primary Antibody
-
anti-Histone Deacetylase 1 (HDAC1) antibody
KO Validated HDAC1 适用: 人 WB, IF, IP, IHC (p), ICC, ChIP, IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal E22 unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 ELISA, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Histone Deacetylase 1 (HDAC1) antibodyKO Validated HDAC1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 207-412) antibodyHDAC1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (C-Term) antibodyVerified HDAC1 适用: 人, 小鼠 WB, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (Middle Region) antibodyHDAC1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (C-Term) antibodyHDAC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Anti-HDAC-1 Antibody has been tested for use in ELISA, immunohistochemistry and western blot. Specific conditions for reactivity should be optimized by the end user. Specific nuclear staining is observed by IHC. Expect bands at 65 kDa in size corresponding to HDAC-1 by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1.33 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
-
-
: "Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs." in: Nature communications, Vol. 9, Issue 1, pp. 1698, (2018) (PubMed).
: "Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma." in: British journal of cancer, Vol. 108, Issue 8, pp. 1648-58, (2013) (PubMed).
: "ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain." in: Oncogene, Vol. 23, Issue 46, pp. 7601-10, (2004) (PubMed).
-
: "Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs." in: Nature communications, Vol. 9, Issue 1, pp. 1698, (2018) (PubMed).
-
- 抗原
- HDAC1 (Histone Deacetylase 1 (HDAC1))
- 别名
- HDAC-1 (HDAC1 产品)
- 背景
-
HDAC-1 antibody recognizes HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) which belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Synonyms: GON 10 antibody, HD 1 antibody, hdac1: histone deacetylase 1 antibody, Histone deacetylase 1 (HD1) antibody, Histone deacetylase 1 antibody, RPD3 (reduced potassium dependency yeast homolog) like 1 antibody - 基因ID
- 3065, 13128860
- UniProt
- Q13547
- 途径
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
-
