Swi6 (AA 314-328) 抗体
适用: Schizosaccharomyces pombe
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
2 images
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- 抗原
- Swi6
- 抗原表位
- AA 314-328
- 适用
- Schizosaccharomyces pombe
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Western Blotting (WB), ELISA
- 免疫原
- This anti-Swi6 Antibody was prepared from whole rabbit antiserum produced by repeated immunizations with a synthetic peptide corresponding aa 314-328 of S.pombe Swi6 protein.
- 亚型
- IgG
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 37 kDa in size corresponding to Swi6 protein by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- Swi6
- 背景
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Swi6 is also known as chromatin-associated swi6 protein and repression of silent mating type loci protein. This protein recognizes and binds to histone H3 tails that are methylated at Lys-9, leading to epigenetic repression. Swi6 is also involved in the repression of the silent mating-type loci MAT2 and MAT3 and it may be resposible for the compaction of MAT2/3 into a heterochromatin-like conformation which represses the transcription of these silent cassettes. Swi6 also interacts with the cohesin subunit psc3. Swi6 has a nuclear localization and contains 2 chromo domains.
Synonyms: Chromatin-associated protein swi6 swi6 ORF Names: SPAC664.01c, SPAC824.10c - 基因ID
- 2541633, 19114361
- UniProt
- P40381
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