ROBO1 抗体 (AA 1632-1644)
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- 抗原 See all ROBO1 抗体
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
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抗原表位
- AA 1632-1644
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ROBO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 交叉反应
- 小鼠, 大鼠, 犬
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1632-1644 of Human ROBO-1.
- 亚型
- IgG
- Top Product
- Discover our top product ROBO1 Primary Antibody
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA , IP, immunohistochemistry, immunofluorescence, and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~181 kDa in size corresponding to ROBO-1 by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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[Auditory neuropathy in children(analysis of 14 cases)]." in: Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, Vol. 19, Issue 1, pp. 19-21, (2006) (PubMed).
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[Auditory neuropathy in children(analysis of 14 cases)]." in: Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, Vol. 19, Issue 1, pp. 19-21, (2006) (PubMed).
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- 抗原
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
- 别名
- ROBO-1 (ROBO1 产品)
- 别名
- DUTT1 antibody, SAX3 antibody, AW494633 antibody, AW742721 antibody, Gm310 antibody, ROBO1 antibody, dutt1 antibody, roundabout antibody, sax3 antibody, MGC122264 antibody, roundabout-1 antibody, roundabout guidance receptor 1 antibody, roundabout, axon guidance receptor, homolog 1 (Drosophila) antibody, roundabout guidance receptor 1 L homeolog antibody, ROBO1 antibody, Robo1 antibody, robo1 antibody, robo1.L antibody
- 背景
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ROBO-1 (also called Roundabout homolog 1 precursor and Deleted in U twenty twenty (DUTT)) functions as a receptor for SLIT1 and SLIT2. The SLIT proteins are thought to act as a molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. ROBO-1 may also be required for lung development. ROBO-1 is a type I membrane protein. ROBO-1 is a widely expressed protein with the exception of the kidney. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO-1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line. Multiple splice variants have been identified for this protein.
Synonyms: ROBO-1, Roundabout homolog 1 precursor, Deleted in U twenty twenty (DUTT) - 基因ID
- 6091
- UniProt
- Q2M1J3
- 途径
- Positive Regulation of Endopeptidase Activity
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