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FANCC 抗体 (AA 80-115)

Rockland 600-401-672 FANCC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN129608
Supplier Product No.: 600-401-672
发货至: 中国
  • 抗原 See all FANCC 抗体
    FANCC (Fanconi Anemia, Complementation Group C (FANCC))
    抗原表位
    • 15
    • 8
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-115
    适用
    • 56
    • 5
    • 2
    宿主
    • 53
    • 3
    克隆类型
    • 54
    • 2
    多克隆
    标记
    • 24
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FANCC antibody is un-conjugated
    应用范围
    • 42
    • 21
    • 19
    • 14
    • 13
    • 13
    • 11
    • 9
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Supplier Product No.
    600-401-672
    Supplier
    Rockland
    原理
    FANCC Antibody
    交叉反应 (详细)
    This affinity-purified antibody is directed against human FANCC protein.
    产品特性
    Synonyms: rabbit anti-FANCC antibody, FANC-C, FANC C, FAC antibody, FACC antibody, Fanconi anemia group C protein, Fanconi anemia complementation group C antibody
    纯化方法
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    过滤
    Sterile filtered
    免疫原

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 80-115 of Human FANCC.

    Immunogen Type: Conjugated Peptide

    亚型
    IgG
    Top Product
    Discover our top product FANCC Primary Antibody
  • 应用备注

    Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 63 kDa in size corresponding to FANCC by western blotting in the appropriate human tissue.

    Western Blot Dilution: 1:1,000 - 1:3,000

    ELISA Dilution: 1:20,000 - 1:80,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.45 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    FANCC (Fanconi Anemia, Complementation Group C (FANCC))
    别名
    FANCC (FANCC 产品)
    背景
    Background: FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function.  FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM.  FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm.  This protein is ubiquitously expressed.  Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.
    基因ID
    2176, 56118236
    UniProt
    Q00597
    途径
    DNA Damage Repair
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