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- 抗原 See all FANCA 抗体
- FANCA (Fanconi Anemia Group A Protein (FANCA))
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抗原表位
- AA 995-1009
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FANCA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- Chimpanzee
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 995-1009 of human FANCA protein.
- 亚型
- IgG
- Top Product
- Discover our top product FANCA Primary Antibody
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a main band at approximately 163 kDa in size corresponding to FANCA by western blotting in the appropriate cell lysate or extract or human tissue.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2.2 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).
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Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).
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- 抗原
- FANCA (Fanconi Anemia Group A Protein (FANCA))
- 别名
- FANCA (FANCA 产品)
- 背景
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FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia
Synonyms: FA 1 antibody, FA antibody, FA H antibody, FA1 antibody, FAA antibody, FACA antibody, FAH antibody, FANCH antibody - 基因ID
- 2175, 66880553
- UniProt
- O15360
- 途径
- DNA Damage Repair
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