电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

FANCA 抗体 (AA 995-1009)

Rockland 600-401-670 FANCA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN129606
Supplier Product No.: 600-401-670
发货至: 中国
  • 抗原 See all FANCA 抗体
    FANCA (Fanconi Anemia Group A Protein (FANCA))
    抗原表位
    • 15
    • 12
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 995-1009
    适用
    • 46
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 58
    • 3
    克隆类型
    • 59
    • 2
    多克隆
    标记
    • 31
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FANCA antibody is un-conjugated
    应用范围
    • 30
    • 23
    • 13
    • 13
    • 10
    • 10
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Supplier Product No.
    600-401-670
    Supplier
    Rockland
    原理
    FANCA Antibody
    交叉反应 (详细)
    This affinity-purified antibody is directed against human FANCA protein.
    产品特性
    Synonyms: rabbit anti-FANCA antibody, FANC-A, FANC A, Fanconi anemia group A protein, FAA antibody, FACA antibody, FAH antibody, FANCH antibody
    纯化方法
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    过滤
    Sterile filtered
    免疫原

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 995-1009 of human FANCA protein.

    Immunogen Type: Conjugated Peptide

    亚型
    IgG
    Top Product
    Discover our top product FANCA Primary Antibody
  • 应用备注

    Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a main band at approximately 163 kDa in size corresponding to FANCA by western blotting in the appropriate cell lysate or extract or human tissue.

    Western Blot Dilution: 1:500 - 1:3,000

    ELISA Dilution: 1:15,000 - 1:60,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.2 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • Smogorzewska, Matsuoka, Vinciguerra, McDonald, Hurov, Luo, Ballif, Gygi, Hofmann, DAndrea, Elledge: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).

  • 抗原
    FANCA (Fanconi Anemia Group A Protein (FANCA))
    别名
    FANCA (FANCA 产品)
    背景
    Background: FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Diseases associated with FANCA include Fanconi anemia complementation group a and Congenital Hypoplastic Anemia.
    基因ID
    2175, 66880553
    UniProt
    O15360
    途径
    DNA Damage Repair
You are here:
客服