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ATF3 抗体 (Internal Region)

Rockland 600-401-493 ATF3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN129602
Supplier Product No.: 600-401-493
发货至: 中国
  • 抗原 See all ATF3 抗体
    ATF3 (Activating Transcription Factor 3 (ATF3))
    抗原表位
    • 16
    • 12
    • 11
    • 8
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 68
    • 32
    • 30
    • 4
    • 4
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    • 2
    • 2
    • 1
    宿主
    • 58
    • 11
    克隆类型
    • 57
    • 12
    多克隆
    标记
    • 37
    • 4
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    • 3
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    • 1
    • 1
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    This ATF3 antibody is un-conjugated
    应用范围
    • 52
    • 28
    • 26
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
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    Western Blotting (WB), ELISA
    Supplier Product No.
    600-401-493
    Supplier
    Rockland
    原理
    ATF3 Antibody
    交叉反应 (详细)
    This affinity-purified antibody is directed against human ATF3 and is useful in determining its presence in various assays including ELISA and western blotting. This polyclonal antibody recognizes over-expressed ATF3 protein found in various expression systems.
    产品特性
    Synonyms: rabbit anti-ATF3 Antibody, ATF 3, Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3
    纯化方法
    Affinity purified antibody
    过滤
    Sterile filtered
    免疫原

    Immunogen: This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human ATF3.

    Immunogen Type: Conjugated Peptide

    亚型
    IgG
    Top Product
    Discover our top product ATF3 Primary Antibody
  • 应用备注

    Application Note: Affinity purified anti-ATF3 has been tested by ELISA and western blotting against recombinant forms of the protein. Although not tested, this antibody is likely function in most immunoassays including immunofluorescence microscopy, immunohistochemistry.

    Western Blot Dilution: 1:200 - 1:2000

    ELISA Dilution: 1:5,000 - 1:20,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • Xie, Xu, Wu, Shen, Zhao, Du, Lv, Gu, Pan, Xu, Xie, Li: "Involvement of CYR61 and CTGF in the fascin-mediated proliferation and invasiveness of esophageal squamous cell carcinomas cells." in: The American journal of pathology, Vol. 176, Issue 2, pp. 939-51, (2010) (PubMed).

  • 抗原
    ATF3 (Activating Transcription Factor 3 (ATF3))
    别名
    ATF3 (ATF3 产品)
    背景
    Background: ATF3, or Activating Transcription Factor 3, is a member of mammalian activation TF/CREB protein family of transcription factors. ATF3 binds the cAMP response element (cre) (consensus: 5'-gtgacgt[ac][ag]-3'), a sequence present in many viral and cellular promoters. However, ATF3 represses rather than activates transcription from promoters with ATF sites stabilizing inhibitory co-factors at the promoter.  Alternate splicing forms of ATF3, called ATF3 delta Zip, lack the leucine zipper domain and do not bind DNA.  ATF3 delta Zip stimulates transcription, presumably by sequestering inhibitory co-factors away from the promoter.  Human ATF3 (SwissProt 18847) is a 20575 Da protein composed of 181 amino acids.
    基因ID
    467
    NCBI登录号
    NP_001025458
    UniProt
    P18847
    途径
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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