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Aurora Kinase B 抗体 (AA 225-250)

Name: Aurora Kinase B 抗体 (AA 225-250)
SKU: ABIN129590
Availability: OutOfStock

Rockland 600-401-465 AURKB 适用: 人 WB, ELISA, FM 宿主: 兔 Polyclonal unconjugated

Image no. 1 for anti-Aurora Kinase B (AURKB) (AA 225-250) antibody (ABIN129590) (Aurora Kinase B 抗体 (AA 225-250))

1 image

(1 reference)

产品编号 ABIN129590

Supplier Product No.: 600-401-465

发货至: 中国

Datasheet as PDF

抗原 See all Aurora Kinase B (AURKB) 抗体

Aurora Kinase B (AURKB)
抗原表位
20

19

13

11

10

8

8

7

6

5

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 225-250
适用
116

65

33

14

4

4

2

1

1

1

1

1
人
宿主
112

23

3

1
兔
Compatible Secondaries
克隆类型
100

40
多克隆
标记
79

10

7

6

4

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Aurora Kinase B antibody is un-conjugated
应用范围
83

58

43

34

16

14

14

13

8

6

4

3

3

3

2

2

1

1

1
Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Supplier Product No.

600-401-465

Supplier

Rockland

原理

AURORA KINASE B Antibody

交叉反应（详细）

Reactivity occurs against human Aurora Kinase B protein.

产品特性

Synonyms: rabbit anti-Aurora B Antibody, AIK2 antibody, AIM1 antibody, ARK2 antibody, AurB antibody, AURKB antibody, Aurora 1 antibody, Aurora and Ipl1 like midbody associated protein 1 antibody

纯化方法

Aurora B antibody is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

过滤

Sterile filtered

免疫原

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 225-250 of Human Aurora Kinase B protein.
Immunogen Type: Conjugated Peptide

亚型

IgG

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anti-Aurora Kinase B (AURKB) (pThr232) antibody
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anti-Aurora Kinase B (AURKB) (AA 1-255) antibody
AURKB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Aurora Kinase B (AURKB) (AA 89-251) antibody
AURKB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal AURKB-1592 unconjugated

anti-Aurora Kinase B (AURKB) (pThr232) antibody
AURKB 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Application Note: Anti-Aurora B is affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 39 kDa in size corresponding to Aurora Kinase B by western blotting in the appropriate cell lysate or extract. Human brain tissue lysate or HeLa cell lysate can be used as a positive control.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:5,000 - 1:20,000
IF Microscopy Dilution: User Optimized
Other: User Optimized

限制

仅限研究用
状态

Liquid

浓度

1.39 mg/mL

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store Anti-Aurora B at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

12 months
Slawson, Lakshmanan, Knapp, Hart: "A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4130-40, (2008) (PubMed).
抗原

Aurora Kinase B (AURKB)

别名

AURKB (AURKB 产品)

背景

Background: Aurora Kinase B (also known as Aurora- and Ipl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, and Aurora-B) is a Ser/Thr protein kinase member of the Aurora subfamily that may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Aurora Kinase B is localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis and is colocalized with gamma tubulin in the mid-body. High levels of Aurora B expression are seen in the thymus, although it is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G₂/M phase and expression is up-regulated in cancer cells during M phase.

基因ID

9212, 83776600

UniProt

Q96GD4

途径

TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades