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NCS1 抗体

Rockland 600-401-216 NCS1 适用: 小鼠 WB, ELISA, IF, MA, FM 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN129571
Supplier Product No.: 600-401-216
发货至: 中国
  • 抗原 See all NCS1 抗体
    NCS1 (Neuronal Calcium Sensor 1 (NCS1))
    适用
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    小鼠
    宿主
    • 63
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    克隆类型
    • 63
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    多克隆
    标记
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    This NCS1 antibody is un-conjugated
    应用范围
    • 55
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Multiplex Assay (MA), Fluorescence Microscopy (FM)
    Supplier Product No.
    600-401-216
    Supplier
    Rockland
    原理
    Frequenin Antibody
    交叉反应 (详细)
    Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.
    产品特性
    Synonyms: rabbit anti-FREQUENIN antibody, NCS-1, FLUP, FREQ, Neuronal calcium sensor 1, frequenin homolog antibody, Frequenin-like protein antibody, NCS 1 antibody, NCS1 antibody
    纯化方法
    This product was prepared from monospecific antiserum by immunoaffinity chromatography using Frequenin (recombinant) coupled to agarose beads.
    过滤
    Sterile filtered
    免疫原

    Immunogen: Frequenin (recombinant from Mouse with extensive post-translational modifications)

    Immunogen Type: Recombinant Protein

    亚型
    IgG
    Top Product
    Discover our top product NCS1 Primary Antibody
  • 应用备注

    Application Note: This product was assayed by immunoblot and found to be reactive against Frequenin at a dilution of 1:5000 followed by reaction with Peroxidase conjugated Affinity Purified anti-Rabbit IgG [H&L] (Goat) code #611-1302.  Anti-Frequenin is suitable for the detection by immunoblot of human, mouse and rat Frequenin. Anti-Frequenin has also been tested for use in IF using Hippocampal neurons of 17 day old NMRI mice.

    Western Blot Dilution: 1:500- 1:2,000

    ELISA Dilution: 1:10,000 - 1:50,000

    IF Microscopy Dilution: 1:100-1:2500

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.0 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    NCS1 (Neuronal Calcium Sensor 1 (NCS1))
    别名
    Ncs1 (NCS1 产品)
    背景
    Background: Frequenin, or Neuronal calcium sensor, is a regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. It directly regulates GRK1 (RHOK), but not GRK2 to GRK5. It can substitute for calmodulin and it stimulates PI4KB kinase activity. It is involved in long-term synaptic plasticity through its interaction with PICK1. Ncs1 may also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
    基因ID
    14299
    NCBI登录号
    NP_062655
    UniProt
    Q8BNY6
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