ING3 抗体 (AA 285-310)
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- 抗原 See all ING3 抗体
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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抗原表位
- AA 285-310
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This ING3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- Supplier Product No.
- 600-101-283
- Supplier
- Rockland
- 原理
- p47ING3 Antibody
- 交叉反应 （详细）
- Reactivity occurs against human p47 ING3 protein.
- 产品特性
- Synonyms: goat anti-p47 ING3 antibody, p47ING3, ING-3, ING 3, Inhibitor of growth family member 3 antibody, Inhibitor of growth protein 3 antibody
- 纯化方法
- This is an affinity-purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: This affinity purified antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 285-310 of Human ING3 protein (Inhibitor of growth family, member 3).
Immunogen Type: Conjugated Peptide
- 亚型
- IgG
- Top Product
- Discover our top product ING3 Primary Antibody
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anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) antibody
ING3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 51-223) antibodyING3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (Internal Region) antibodyING3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) antibodyING3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) antibodyING3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) antibodyING3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E21 unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 216-265) antibodyING3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 小鸡, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 36-85) antibodyING3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) antibodyING3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) antibodyING3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Specific conditions for western blotting reactivity should be optimized by the end user. Expect a band at approximately 47 kDa in size corresponding to ING3 isoform 1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:200 - 1:2,000
ELISA Dilution: 1:10,000 - 1:40,000
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.10 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
- 别名
- ING3 (ING3 产品)
- 背景
- Background: p47 ING3 is a tumor suppressor protein similar to ING1 that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Over-expression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Multiple alternatively spliced transcript variants have been observed. The accession number listed below is for variant (1) that encodes the longest isoform.
- 基因ID
- 54556, 38201655
- UniProt
- Q9NXR8
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