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MTBP 抗体 (AA 667-812)

MTBP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal PHL-1 unconjugated
产品编号 ABIN129549
发货至: 中国
  • 抗原 See all MTBP 抗体
    MTBP (MDM2 Binding Protein (MTBP))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 667-812
    适用
    • 39
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 1
    小鼠
    克隆类型
    • 39
    • 1
    单克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTBP antibody is un-conjugated
    应用范围
    • 34
    • 14
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    交叉反应
    Chimpanzee
    纯化方法
    ASCITES
    免疫原
    This protein A purified monoclonal antibody was produced by repeated immunizations with a recombinant amino-terminal HIS6X-tagged polypeptide corresponding to amino acid residues 667-812 of human MTBP protein.
    克隆位点
    PHL-1
    Top Product
    Discover our top product MTBP Primary Antibody
  • 应用备注
    This antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 110 kDa in size corresponding to MTBP by western blotting in the appropriate cell lysate or extract.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    MTBP (MDM2 Binding Protein (MTBP))
    别名
    MTBP (MTBP 产品)
    别名
    MDM2BP antibody, AI429604 antibody, MDM2 binding protein antibody, Mdm2, transformed 3T3 cell double minute p53 binding protein antibody, MTBP antibody, Mtbp antibody
    背景
    The MDM2 onco-protein is over expressed in human cancer cells and it promotes tumorigenesis by directly blocking the function of the p53 tumor suppressor.  Studies also indicate that MDM2 regulates cell prolifer-ation via p53 independent mechanisms.   MTBP (Mdm2 [Two] Binding Protein) was identified by a yeast two-hybrid screen as an MDM2 binding protein (1).  MTBP has been reported to modulate cell cycle progression by a p53 independent mechanism and suppress MDM2-mediated p53 degradation when ectopically expressed in cells (1,2).   The human MTBP gene localizes to 8q24 (3) and MTBP RNA is expressed in a wide range of tissues, with highest being in the thymus, testes and ovaries (1).
    Synonyms: MDM 2 BP antibody, MDM2 (mouse double minute 2) binding protein 104kD antibody, MDM2 (mouse double minute 2) binding protein antibody, MDM2 Binding Protein antibody, MDM2 BP antibody
    基因ID
    27085
    NCBI登录号
    NP_071328
    UniProt
    Q96DY7
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