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- 抗原 See all S100 Protein (S100) 抗体
- S100 Protein (S100)
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适用
- Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
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This Protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full-length bovine S100 protein (mixture of aa homodimers and ab heterodimers).
Immunogentype:Native - 亚型
- IgG
- Top Product
- Discover our top product S100 Primary Antibody
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anti-S100 Protein (S100) (AA 2-94) antibody
S100 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Protein (S100) (AA 1-94) antibodyS100 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Protein (S100) (AA 1-94) antibodyS100 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-S100 Protein (S100) (AA 1-94) antibodyS100 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-S100 Protein (S100) (AA 1-94) antibodyS100 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This Protein A purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 11 kDa in size corresponding to S100 monomer by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Restore with deionized water (or equivalent)
- 浓度
- 5.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- S100 Protein (S100)
- 别名
- S100 Protein (S100 产品)
- 别名
- S100 antibody, S100-alpha antibody, S100A antibody, NEF antibody, S100-B antibody, S100beta antibody, S100A1 antibody, AI266795 antibody, S100a antibody, S100 calcium binding protein A1 antibody, S100 calcium binding protein B antibody, S100 calcium binding protein A13 antibody, S100A1 antibody, S100B antibody, S100a1 antibody, S100a13 antibody
- 背景
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S-100 protein derived from brain tissue is an acidic calcium-binding protein with molecular weight of about 21kDa. In human brain tissue S-100 protein is mainly presented as two isoforms - bb homodimer (S-100b) and ab heterodimer (S-100a). Because of its predominant location in astroglial cells S-100 protein can be used as a sensitive and reliable marker for central nervous system injury. Structural damage of glial cells causes leakage of S-100 protein into the extracellular matrix and into cerebrospinal fluid, further releasing into the bloodstream. Measurements of S-100 protein in patient serum samples are useful in monitoring of traumatic brain injury, ischemic brain damage after circulatory arrests, and in diagnosis and prognosis of clinical outcome in acute stroke. Although predominant among the water-soluble brain proteins, S-100 is also found in a variety of other tissues. S-100 is an intracellular protein that weakly binds calcium. It binds zinc very tightly, however, and this appears to increase the affinity of the protein for calcium. Distinct binding sites, with different affinities, exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
Synonyms: S100 calcium-binding protein A1 S-100 protein subunit alpha S-100 protein alpha chain - 基因ID
- 6271, 30582715
- UniProt
- P02639
- 途径
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
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