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- 抗原 See all PMS2 抗体
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PMS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- Supplier Product No.
- 200-301-864
- Supplier
- Rockland
- 原理
- PMS2 Antibody
- 交叉反应 （详细）
- The epitope was putatively mapped to amino acids 58-81 of human PMS2.
- 产品特性
- Synonyms: mouse anti-PMS2 antibody, DNA mismatch repair gene homologue antibody, H_DJ0042M02.9 antibody, HNPCC4 antibody, PMS 2 antibody, PMS1 protein homolog 2 antibody, PMS2 postmeiotic segregation increased 2 antibody, PMS2CL antibody, PMSL2 antibody
- 纯化方法
- This is an protein A purified antibody from ascites fluid directed against PMS2-134 and reacts with full length version of PMS2 in human and hamster tissues.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: This protein A purified monoclonal antibody was produced by repeated immunizations with recombinant human PMS2 corresponding to the first 133 amino acid residues of the protein. The clone was produced using conventional hybridoma technology.
Immunogen Type: Recombinant Protein
- 克隆位点
- 1204
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product PMS2 Primary Antibody
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anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) antibody
PMS2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6G12E1 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 748-851) antibodyPMS2 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8E4G11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 748-851) antibodyPMS2 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E9D11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 748-851) antibodyPMS2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6A12H9 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-862) antibodyPMS2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 763-862) antibodyPMS2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 390-670) antibodyPMS2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 1-862) antibodyPMS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 763-862) antibodyPMS2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4A8 unconjugated
anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (C-Term) antibodyPMS2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: Anti-PMS2 antibody has been tested for use in ELISA and western blotting. This product is suitable for immunoprecipitation. Specific conditions for western blotting reactivity should be optimized by the end user. Expect a band approximately 96 kDa in size corresponding to human PMS2 by western blotting in most cell lines and tissues as PMS2 is ubiquitously expressed.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:5,000 - 1:20,000
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.38 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
- 别名
- PMS2 (PMS2 产品)
- 背景
- Background: PMS2 is a highly conserved nuclear protein involved in mismatch repair during DNA replication and has been identified to be composed as a heterodimer of PMS2 and MLH1. PMS is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. This association could be a dynamic process changing throughout the cell cycle and within subnuclear domains. Defects in PMS2 are the cause of hereditary non-polyposis colorectal cancer type 4 (HNPCC4), Turcot syndrome (an autosomal dominant disorder characterized by malignant tumors of the brain associated with multiple colorectal adenomas) and supratentorial primitive neuroectodermal tumors with cafe-au-lait spots (SNTCL). The human PMS2 gene encodes an 862 aa, 96 kDa polypeptide.
- 基因ID
- 5395
- UniProt
- P54278
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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