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Insulin 抗体

INS 适用: 人 IHC, WB, ELISA, IP 宿主: 小鼠 Monoclonal 2D11-H5 unconjugated
产品编号 ABIN129507
发货至: 中国
  • 抗原 See all Insulin (INS) 抗体
    Insulin (INS)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Insulin antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This protein A purified monoclonal antibody was produced by repeated immunizations with purified human insulin coupled to bovine serum albumin (BSA).
    Immunogentype:Native
    克隆位点
    2D11-H5
    亚型
    IgG
    Top Product
    Discover our top product INS Primary Antibody
  • 应用备注
    This antibody is suitable for ELISA, immunohistochemistry, immunoblotting and immunoprecipitation. Insulin has a cytoplasmic localization.  Pancreatic tissue or b-cells from islets of Langerhans can be used as a positive control.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    Insulin (INS)
    别名
    Insulin (INS 产品)
    背景
    Recognizes the 51 amino acid (6 kDa) insulin polypeptide composed of A and B chains. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-peptide basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain acids. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.  The main storage site for insulin is the pancreatic islets.  Antibodies to insulin are important as b-cell and tumor (insulinoma) markers).
    Synonyms: ILPR antibody, INS antibody, Insulin A chain antibody, Insulin B chain antibody, Insulin precursor antibody, IRDN antibody, Proinsulin antibody, Proinsulin precursor antibody
    基因ID
    3630
    UniProt
    P01308
    途径
    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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