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- 抗原 See all LRP5 抗体
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRP5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
- 纯化方法
- Affinity Chromatography
- 免疫原
- Synthetic peptide surrounding amino acid 437 of Human LRP.
- 亚型
- IgG
- Top Product
- Discover our top product LRP5 Primary Antibody
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- 应用备注
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Western Blot: 0.5-4.0 μg/mL. Jurkat cell lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal as preservative
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C/-80 °C
- 储存方法
- Store the antibody undiluted at -20 °C or at -70 °C (in aliquots) for long term storage.
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Inhibition of Hepatitis C Virus in Mice by a Small Interfering RNA Targeting a Highly Conserved Sequence in Viral IRES Pseudoknot." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146710, (2016) (PubMed).
: "Hypoxia-mediated impairment of the mitochondrial respiratory chain inhibits the bactericidal activity of macrophages." in: Infection and immunity, Vol. 80, Issue 4, pp. 1455-66, (2012) (PubMed).
: "Coordinated action of CK1 isoforms in canonical Wnt signaling." in: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2877-88, (2011) (PubMed).
: "A p120-catenin-CK1epsilon complex regulates Wnt signaling." in: Journal of cell science, Vol. 123, Issue Pt 15, pp. 2621-31, (2010) (PubMed).
: "Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration." in: American journal of physiology. Cell physiology, Vol. 298, Issue 3, pp. C550-8, (2010) (PubMed).
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Inhibition of Hepatitis C Virus in Mice by a Small Interfering RNA Targeting a Highly Conserved Sequence in Viral IRES Pseudoknot." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146710, (2016) (PubMed).
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- 抗原
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
- 别名
- LRP5 + LRP6 (LRP5 产品)
- 别名
- Xlrp5 antibody, bmnd1 antibody, evr1 antibody, evr4 antibody, hbm antibody, lr3 antibody, lrp5-A antibody, lrp7 antibody, oppg antibody, ops antibody, opta1 antibody, vbch2 antibody, LRP5 antibody, LRP6 antibody, BMND1 antibody, EVR1 antibody, EVR4 antibody, HBM antibody, LR3 antibody, LRP7 antibody, OPPG antibody, OPS antibody, OPTA1 antibody, VBCH2 antibody, mKIAA4142 antibody, low-density lipoprotein receptor-related protein 5 antibody, LDL receptor related protein 5 antibody, LDL receptor related protein 5 L homeolog antibody, low density lipoprotein receptor-related protein 5 antibody, LDL receptor related protein 5 like antibody, LOC100147353 antibody, LRP5 antibody, lrp5.L antibody, lrp5 antibody, Lrp5 antibody, LRP5L antibody
- 背景
- LDL-related proteins LRP-5 and LRP-6. are members of the LDL receptor superfamily, which were found to be involved in the canonical Want signaling pathway. Mammalian LRP-6 was shown to bind to Wnt-1 and enhance Induced-induced developmental processes in Xenopus embryos. Mice lacking LRP-6 exhibited developmental defects that are similar to those caused by deficiencies in various Want proteins. Recent work also shows that Want proteins induce the binding of LRP-5 to Axin, leading Axin degradation and beta-catenin stabilization.Synonyms: LRP5, LRP6, LRP7, Low-density lipoprotein receptor-related protein 5, Low-density lipoprotein receptor-related protein 6
- 途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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