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HDAC6 抗体 (N-Term)

HDAC6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127242
发货至: 中国
  • 抗原 See all HDAC6 抗体
    HDAC6 (Histone Deacetylase 6 (HDAC6))
    抗原表位
    • 26
    • 15
    • 11
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    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    N-Term
    适用
    • 124
    • 45
    • 32
    • 9
    • 5
    • 4
    • 3
    • 3
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    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 109
    • 18
    • 1
    克隆类型
    • 102
    • 26
    多克隆
    标记
    • 73
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 2
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    • 2
    • 2
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    • 1
    • 1
    This HDAC6 antibody is un-conjugated
    应用范围
    • 98
    • 38
    • 37
    • 28
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    • 20
    • 14
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    • 11
    • 6
    • 5
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody detects ~134 kDa HDAC-6. This antibody does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 5, 7, and 8.
    纯化方法
    Affinity Chromatography.
    免疫原
    Synthetic peptide mapping to the N-terminus of mouse HDAC-6.
    Top Product
    Discover our top product HDAC6 Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 20 μg/mL. Positive Control: Mouse small intestine tissue lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % thimerosal.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for longer.
  • 抗原
    HDAC6 (Histone Deacetylase 6 (HDAC6))
    别名
    HDAC6 (HDAC6 产品)
    背景
    Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.Synonyms: HD6, Histone deacetylase 6, JM21, KIAA0901
    基因ID
    10013
    NCBI登录号
    NP_006035
    UniProt
    Q9UBN7
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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