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Transferrin Receptor 抗体 (FITC)

TFRC 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-75 FITC
产品编号 ABIN120701
发货至: 中国
  • 抗原 See all Transferrin Receptor (TFRC) 抗体
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    适用
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    宿主
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    小鼠
    克隆类型
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    • 94
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    单克隆
    标记
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    This Transferrin Receptor antibody is conjugated to FITC
    应用范围
    • 145
    • 133
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    Flow Cytometry (FACS)
    免疫原
    Pre-B cell line NALM-6
    克隆位点
    MEM-75
    亚型
    IgG1
    Top Product
    Discover our top product TFRC Primary Antibody
  • 应用备注
    Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL whole blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    别名
    CD71 / TFRC (TFRC 产品)
    背景
    CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH . CD71 is also involved in uptake of non-transferrin bound iron.Synonyms: TfR1, Transferrin receptor protein 1, p90
    UniProt
    P02786
    途径
    Transition Metal Ion Homeostasis
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