TLR4 抗体
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- 抗原 See all TLR4 抗体
- TLR4 (Toll-Like Receptor 4 (TLR4))
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适用
- 人, 犬, Pig, 豚鼠, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TLR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- 纯化方法
- Affinity chromatography on Protein G
- 内毒素水平
- < 0.01 EU/ug
- 免疫原
- Ba/F3 cell line expressing TLR4 (CD284). Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
- 克隆位点
- HTA125
- 亚型
- IgG2a
- Top Product
- Discover our top product TLR4 Primary Antibody
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- 应用备注
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Flow Cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, None, None
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
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- 抗原
- TLR4 (Toll-Like Receptor 4 (TLR4))
- 别名
- CD284 / TLR4 (TLR4 产品)
- 背景
- TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.Synonyms: Toll-like receptor 4
- NCBI登录号
- NM_138554
- UniProt
- O00206
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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