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MHC Class II HLA-DP/DQ/DR 抗体 (FITC)

HLA-DP/DQ/DR 适用: 人 FACS 宿主: 小鼠 Monoclonal WR18 FITC
产品编号 ABIN118903
发货至: 中国
  • 抗原 See all MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) products
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    适用
    • 23
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    宿主
    • 21
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    小鼠
    克隆类型
    • 23
    单克隆
    标记
    • 12
    • 6
    • 3
    • 2
    This MHC Class II HLA-DP/DQ/DR antibody is conjugated to FITC
    应用范围
    • 21
    • 8
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    Flow Cytometry (FACS)
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Human HLA Class II. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS.0 myeloma cell line.
    克隆位点
    WR18
    亚型
    IgG2a
  • 应用备注
    Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilzer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    别名
    HLA Class II DP, DR, DQ (HLA-DP/DQ/DR 产品)
    背景
    The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II. The antigen is expressed by B lymphocytes, monocytes and activated T lymphocytes.Synonyms: DQ, DR, HLA class II histocompatibility antigen DP, MHC class II antigen DP
    途径
    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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