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CD44 抗体 (AA 3-10) (FITC)

Name: CD44 抗体 (AA 3-10) (FITC)
SKU: ABIN118683
Availability: OutOfStock

CD44 适用: 人 FACS 宿主: 小鼠 Monoclonal VFF-7 FITC

产品编号 ABIN118683

发货至: 中国

Datasheet as PDF

抗原 See all CD44 抗体

CD44
抗原表位
16

16

16

10

8

5

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 3-10
适用
279

137

73

32

25

23

15

13

10

9

8

7

7

5

5

4

2

2

1

1

1

1

1
人
宿主
180

110

72

2

1
小鼠
Compatible Secondaries
克隆类型
258

105

2
单克隆
标记
165

45

32

23

18

7

6

5

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This CD44 antibody is conjugated to FITC
应用范围
273

149

91

71

70

68

56

41

40

30

24

15

7

6

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

特异性

This antibody specifically recognises an epitope encoded by exon v6 on the variant portion of Human CD44.

交叉反应（详细）

Species reactivity (tested):Human.

免疫原

Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of Human CD44. Spleen cells from immunised BALB/c micewere fused with cells of the P3X63Ag8.653 myeloma cell line.

克隆位点

VFF-7

亚型

IgG1

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应用备注

Flow cytometry: Use 10 μL to label 10^6 Cells/100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.1 mg/mL

缓冲液

Tris buffered saline containing 0.02 % Sodium Azide as preservative and 1 % BSA as stabilizer.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

CD44

别名

CD44 (CD44 产品)

别名

CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, XCD44 antibody, cd44 antibody, cdw44 antibody, cspg8 antibody, ecmr-iii antibody, hcell antibody, lhr antibody, mc56 antibody, mdu2 antibody, mdu3 antibody, mic4 antibody, mutch-i antibody, pgp1 antibody, CD44 molecule (Indian blood group) antibody, syndecan 4 antibody, CD44 antigen antibody, CD44 molecule (Indian blood group) S homeolog antibody, CD44 antibody, SDC4 antibody, Cd44 antibody, cd44.S antibody

背景

CD44 is the receptor for hyaluronic acid (HA). It mediates cell to cell and cell matrix interactions through its affinity for HA. Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. High protein heterogeneity due to several alternative splicing and post translational modification events. CD44R represents a heterogeneous group of CD44 variant isoforms expressed constitutively in epithelial cells and monocyte lineage cells and can be upregulated in activated leukocytes. CD44R, and in particular CD44v6 containing isoforms, may be involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to sites of inflammation. CD44v6 containing isoforms may be involved in tumor metastasis.Synonyms: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein I

基因ID

960

NCBI登录号

NP_000601

UniProt

P16070

途径

Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling