电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CD27 抗体

CD27 适用: 人 FACS 宿主: 小鼠 Monoclonal LT27 unconjugated
产品编号 ABIN118578
发货至: 中国
  • 抗原 See all CD27 抗体
    CD27 (CD27 Molecule (CD27))
    适用
    • 168
    • 64
    • 43
    • 9
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 108
    • 75
    • 22
    • 3
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 119
    • 91
    • 2
    单克隆
    标记
    • 78
    • 21
    • 20
    • 14
    • 10
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD27 antibody is un-conjugated
    应用范围
    • 135
    • 71
    • 48
    • 32
    • 30
    • 18
    • 17
    • 14
    • 13
    • 13
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    The antibody reacts with CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Precipitation methods and ion exchange chromatography
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human peripheral blood lymphocytes
    克隆位点
    LT27
    亚型
    IgG2a
    Top Product
    Discover our top product CD27 Primary Antibody
  • 应用备注
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Dilute only prior to immediate use
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD27 (CD27 Molecule (CD27))
    别名
    CD27 (CD27 产品)
    背景
    CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7
    基因ID
    939
    NCBI登录号
    NP_001233
    UniProt
    P26842
    途径
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
You are here:
客服