CD14 抗体
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- 抗原 See all CD14 抗体
- CD14
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适用
- 人, 猴, Pig, Cow, 绵羊, 犬, 山羊, Cat, 兔, Mink
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD14 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Enzyme Immunoassay (EIA)
- 交叉反应 (详细)
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Species reactivity (expected):Canine, Goat, Cat, Rabbit, Mink, Bovine, Porcine,Sheep, Cynomolgus Monkey, Llama.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography on Protein G.
- 克隆位点
- Tük4
- 亚型
- IgG2a
- Top Product
- Discover our top product CD14 Primary Antibody
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- 应用备注
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Flow cytometry: 1/50 - 1/200, use 5 μL of suggested working dilution to label 10^6 cells or 100 μL whole blood. ELISA. Western Blot under reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CD14
- 别名
- CD14 (CD14 产品)
- 别名
- CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
- 背景
- CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidyl-inositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
- 基因ID
- 9606
- UniProt
- P08571
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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