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CD38 抗体

适用: 小鼠 FACS, IP, IHC (fro) 宿主: 大鼠 Monoclonal 9E1 unconjugated
产品编号 ABIN118188
发货至: 中国
  • 抗原 See all CD38 抗体
    CD38
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CD38 antibody is un-conjugated
    应用范围
    • 173
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises the CD38 cell surface antigen.
    纯化方法
    Purified
    免疫原
    Mouse pre-B cells derived from IL-7 dependent bone marrow cultures
    克隆位点
    9E1
    亚型
    IgG2a
    Top Product
    Discover our top product CD38 Primary Antibody
  • 应用备注
    Flow cytometry: 1/2- 1/20, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS containing 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    CD38
    Abstract
    CD38 产品
    背景
    CD38 (T10) is a single chain 42 to 46 kDa type II integral transmembrane glycoprotein with a short N terminal cytoplasmic tail. CD38 is highly expressed on thymocytes. It is also expressed by early cells of B and T lineages, NK cells, plasma cells, monocytes and macrophages and may be detected on cells from multiple myeloma, ALL (B and T) and some AML. It is expressed by murine, but not human, hematopoietic progenitors. In normal lymph nodes and tonsils the antigen is detected mainly on B cells in germinal centers and in plasma cells. The extracellular domain of the molecule shares a high homology sequence with Aplysia ADP ribosyl cyclase. CD38 functions as a multicatalytic ectoenzyme serving as ADP ribosyl cyclase, ADPR hydrolase and possibly NAD+ glycohydrolase, or as a surface receptor.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1
    基因ID
    12494
    NCBI登录号
    NP_031672
    UniProt
    P56528
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