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Aurora Kinase B 抗体 (AA 227-238)

Name: Aurora Kinase B 抗体 (AA 227-238)
SKU: ABIN117978
Availability: OutOfStock

AURKB 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated

Figure shows a model of Aurora B, INCENP, and Survivin interactions and regulation. (Aurora Kinase B 抗体 (AA 227-238))

1 image

(1 reference)

产品编号 ABIN117978

发货至: 中国

Datasheet as PDF

抗原 See all Aurora Kinase B (AURKB) 抗体

Aurora Kinase B (AURKB)
抗原表位
20

19

17

14

10

8

8

7

6

6

5

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 227-238
适用
125

68

35

13

4

4

2

1

1

1

1

1
人
宿主
121

23

3

1
兔
Compatible Secondaries
克隆类型
109

40
多克隆
标记
83

11

8

7

5

5

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Aurora Kinase B antibody is un-conjugated
应用范围
92

66

43

36

17

14

14

13

8

6

4

3

3

3

2

2

1

1
Western Blotting (WB), Enzyme Immunoassay (EIA)

序列

Human Aurora B Kinase, 344 aa, predicted MW 39.3kDa 1 maqkensypw pygrqtapsg lstlpqrvlr kepvtpsalv lmsrsnvqpt aapgqkvmen 61 ssgtpdiltr hftiddfeig rplgkgkfgn vylarekksh fivalkvlfk sqiekegveh 121 qlrreieiqa hlhhpnilrl ynyfydrrri ylileyaprg elykelqksc tfdeqrtati 181 meeladalmy chgkkvihrd ikpenlllgl kgelkiadfg wsvhapslrr ktmcgtldyl 241 ppemiegrmh nekvdlwcig vlcyellvgn ppfesashne tyrrivkvdl kfpasvptga 301 qdliskllrh npserlplaq vsahpwvran srrvlppsal qsva

特异性

This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase. Reactivity occurs against human Aurora Kinase B protein. No reaction is expected against Aurora Kinase A. However, 100 % sequence homology as indicated by BLAST analysis is on record for this protein from human, mouse, rat, cow, pig, dog and chimpanzee. Cross reactivity with Aurora Kinase B from other sources is not known.

纯化方法

Immunoaffinity chromatography.

免疫原

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 227-238 of Human Aurora Kinase B protein.

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anti-Aurora Kinase B (AURKB) (AA 223-234), (pThr232) antibody
AURKB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Aurora Kinase B (AURKB) (AA 1-90) antibody
AURKB 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 6H7 unconjugated

anti-Aurora Kinase B (AURKB) (AA 6-35) antibody
AURKB 适用: 人, 小鼠, 大鼠, 灵长类 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Aurora Kinase B (AURKB) antibody
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anti-Aurora Kinase B (AURKB) (AA 1-90) antibody
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anti-Aurora Kinase B (AURKB) (AA 89-251) antibody
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anti-Aurora Kinase B (AURKB) (pThr232) antibody
AURKB 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Aurora Kinase B (AURKB) (AA 1-255) antibody
AURKB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Aurora Kinase B (AURKB) (AA 89-251) antibody
AURKB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal AURKB-1592 unconjugated

anti-Aurora Kinase B (AURKB) (pThr232) antibody
AURKB 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

This affinity purified antibody has been tested for use in ELISA (1: 5,000-1: 20,000) and byWestern blot (1: 500-1: 2,000). Specific conditions for reactivity should be optimized by theend user. Expect a band approximately 39 kDa in size corresponding to Aurora Kinase B bywestern blotting in the appropriate cell lysate or extract. Human brain tissue lysate or HeLacell lysate can be used as a positive control.

限制

仅限研究用
浓度

0.45 mg/mL (by UV absorbance at 280 nm)

缓冲液

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Dilute only prior to immediate use

储存条件

4 °C/-20 °C

储存方法

Store vial at -20° C prior to opening. This product is stable for one month at 2-8 °C as an undiluted liquid. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
Honda, Asato, Tanaka, Endo, Nishimura, Ito: "Vidian nerve schwannoma with middle cranial fossa extension resected via a maxillary swing approach." in: Head & neck, (2008) (PubMed).
抗原

Aurora Kinase B (AURKB)

别名

Aurora Kinase B (AURKB 产品)

别名

AIK2 antibody, AIM-1 antibody, AIM1 antibody, ARK2 antibody, AurB antibody, IPL1 antibody, PPP1R48 antibody, STK12 antibody, STK5 antibody, aurkb-sv1 antibody, aurkb-sv2 antibody, AIRK2 antibody, AL022959 antibody, Aik2 antibody, Aim1 antibody, Ark2 antibody, STK-1 antibody, Stk12 antibody, Stk5 antibody, Aur B antibody, Aurora B antibody, Aurora-B antibody, CG6620 antibody, DmAIRK2 antibody, DmAurB antibody, DmAuroraB antibody, Dmel\\CG6620 antibody, IAL antibody, IAL1 antibody, Ial antibody, aurB antibody, aurora B antibody, ARK-2 antibody, XAIRK2 antibody, aik2 antibody, aim-1 antibody, aim1 antibody, airk2 antibody, ark2 antibody, ipl1 antibody, stk12 antibody, stk5 antibody, CHUNP6896 antibody, fa09g06 antibody, stka antibody, wu:fa09g06 antibody, aurkb antibody, AIRK2-B antibody, XAIRK2-B antibody, aurkb-a antibody, aurkb-b antibody, xAurora-B-B antibody, aurora kinase B antibody, aurora B antibody, aurora kinase B S homeolog antibody, AURKB antibody, Aurkb antibody, aurB antibody, aurkb antibody, aurkb.S antibody

背景

Aurora Kinase B (also known as Aurora- and Ipl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, and Aurora-B) is a Ser/Thr protein kinase member of the Aurora subfamily that may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Aurora Kinase B is localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis and is colocalized with gamma tubulin in the mid-body. High levels of Aurora B expression are seen in the thymus, although it is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase.Synonyms: AIK2, AIM1, ARK2, AURKB, Aurora- and Ipl1-like midbody-associated protein 1, Aurora-B, Aurora/IPL1-related kinase 2, STK-1, STK12, Serine/threonine-protein kinase 12

基因ID

9212

NCBI登录号

NP_004208

UniProt

Q96GD4

途径

TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades