Cullin 2 抗体 (C-Term)
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- 抗原 See all Cullin 2 (CUL2) 抗体
- Cullin 2 (CUL2)
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抗原表位
- AA 733-745, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cullin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- 序列
- Human Cullin 2 (745 aa 86.9 kDa): 1 mslkprvvdf detwnklltt ikavvmleyv eratwndrfs diyalcvayp eplgerlyte 61 tkiflenhvr hlhkrvlese eqvlvmyhry weeyskgady mdclyrylnt qfikknklte 121 adlqygyggv dmneplmeig elaldmwrkl mveplqaili rmllreiknd rggedpnqkv 181 ihgvinsfvh veqykkkfpl kfyqeifesp fltetgeyyk qeasnllqes ncsqymekvl 241 grlkdeeirc rkylhpssyt kvihecqqrm vadhlqflha echniirqek kndmanmyvl 301 lravstglph miqelqnhih deglratsnl tqenmptlfv esvlevhgkf vqlintvlng 361 dqhfmsaldk altsvvnyre pksvckapel lakycdnllk ksakgmtene vedrltsfit 421 vfkyiddkdv fqkfyarmla krlihglsms mdseeamink lkqacgyeft sklhrmytdm 481 svsadlnnkf nnfiknqdtv idlgisfqiy vlqagawplt qapsstfaip qeleksvqmf 541 elfysqhfsg rkltwlhylc tgevkmnylg kpyvamvtty qmavllafnn setvsykelq 601 dstqmnekel tktikslldv kminhdseke didaessfsl nmnfsskrtk fkittsmqkd 661 tpqemeqtrs avdedrkmyl qaaivrimka rkvlrhnali qevisqsrar fnpsismikk 721 cievlidkqy iersqasade ysyva
- 特异性
- This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human Cullin 2. Cross reactivity with Cul2 from other sources has not been determined.
- 纯化方法
- Delipidation and defibrination.
- 免疫原
- Synthetic peptide corresponding to amino acids 733-745 of Human Cul2 (C-terminus) coupled to KLH.
- Top Product
- Discover our top product CUL2 Primary Antibody
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anti-Cullin 2 (CUL2) (C-Term) antibody
CUL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 591-742) antibodyCUL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 2 (CUL2) antibodyCUL2 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyVerified CUL2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 40-310) antibodyCUL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 264-280), (Middle Region) antibodyCUL2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: This antibody reacts with human Cul2 (1/500-1/1,000, An 86.9 kDa bandcorresponding to human Cul2 is detected). Most cell lines expressing Cul2 can be used asa positive control). Immunoprecipitation: The antibody immunoprecipitates in vitro translated product andprotein from cell lysates (using HeLa or NIH-3T3). ELISA (1/2,000-1/10,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 85.0 mg/mL (by Refractometry)
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for up to one month or at -20 °C for longer.
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- 抗原
- Cullin 2 (CUL2)
- 别名
- Cullin-2 (CUL2 产品)
- 别名
- cul2 antibody, Cullin-2 antibody, fj48a06 antibody, wu:fj48a06 antibody, cullin-2 antibody, LOC100221330 antibody, 1300003D18Rik antibody, 4932411N15Rik antibody, AI327301 antibody, mKIAA4106 antibody, ATCUL2 antibody, F22D16.2 antibody, F22D16_2 antibody, cullin 2 antibody, cullin 2 antibody, cullin-2 antibody, putative cullin-2 (cul-2) antibody, cullin 2 L homeolog antibody, Cullin-2 antibody, cul2 antibody, CUL2 antibody, PTRG_05231 antibody, Smp_079740 antibody, LOC100550749 antibody, Cul2 antibody, cul2.L antibody, cul-2 antibody
- 背景
- Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 2 is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cul2 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul2 may also contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Cul2 is part of the SCF complex consisting of CUL1, RBX1, SKP1 and SKP2, where it interacts directly with SKP1, SKP2 and RBX1. Cul2 also interacts with RNF7 and is part of a complex with TIP120A/CAND1 and RBX1. The unneddylated form interacts with TIP120A/CAND1 and the interaction negatively regulates the association with SKP1 in the SCF complex.Synonyms: CUL-2, CUL2
- 基因ID
- 8453
- NCBI登录号
- NP_001185706
- UniProt
- Q13617
- 途径
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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