TCR beta 抗体
(13 references)-
- 抗原 See all TCR beta 抗体
- TCR beta (T Cell Receptor (TCR) beta (TCR beta))
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适用
- 小鼠
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宿主
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Armenian Hamster
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克隆类型
- 单克隆
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标记
- This TCR beta antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 品牌
- BD Pharmingen™
- 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- 免疫原
- TCR affinity-purified from mouse T-cell hybridoma DO-11.10
- 克隆位点
- H57-597
- 亚型
- IgG2 lambda
- Top Product
- Discover our top product TCR beta Primary Antibody
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anti-T Cell Receptor (TCR) beta (TCR beta) antibody (FITC)
TCR beta 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal H57-597 FITC
anti-T Cell Receptor (TCR) beta (TCR beta) antibody (APC)TCR beta 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal H57-597 APC
anti-T Cell Receptor (TCR) beta (TCR beta) (Internal Region) antibodyTCR beta 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-T Cell Receptor (TCR) beta (TCR beta) antibodyTCR beta 适用: 小鼠 FACS, IP 宿主: 仓鼠 Monoclonal H57-597 unconjugated
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- 应用备注
- Flow cytometry: It has been observed that pre-incubation of thymus cell suspensions at 37°C for 2-4 hours prior to staining enhances the ability of anti-CD3e and anti-TCR beta chain mAbs to detect the T cell receptor on immature thymocytes.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Different initiation of pre-TCR and gammadeltaTCR signalling." in: Nature, Vol. 406, Issue 6795, pp. 524-7, (2000) (PubMed).
: "Mouse NK1.1+ T cells: a new family of T cells." in: Immunology today, Vol. 17, Issue 2, pp. 71-6, (1996) (PubMed).
: "Diversity of V gamma gene segments rearranged to the J gamma 4 gene in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 2, pp. 676-84, (1995) (PubMed).
: "Rapid rejection of H2k and H2k/b bone marrow cell grafts by CD8+ T cells and NK cells in irradiated mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 8, pp. 3742-9, (1995) (PubMed).
: "A subset of CD4+ thymocytes selected by MHC class I molecules." in: Science (New York, N.Y.), Vol. 263, Issue 5154, pp. 1774-8, (1994) (PubMed).
: "Preferential usage of the Fc receptor gamma chain in the T cell antigen receptor complex by gamma/delta T cells localized in epithelia." in: The Journal of experimental medicine, Vol. 179, Issue 1, pp. 365-9, (1994) (PubMed).
: "Analysis and expression of a cloned pre-T cell receptor gene." in: Science (New York, N.Y.), Vol. 266, Issue 5188, pp. 1208-12, (1994) (PubMed).
: "T cell receptor beta chain dimers on immature thymocytes from normal mice." in: European journal of immunology, Vol. 23, Issue 6, pp. 1393-6, (1993) (PubMed).
: "Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 971-84, (1993) (PubMed).
: "Phenotypic complexity of intraepithelial lymphocytes of the small intestine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 6, pp. 1746-51, (1991) (PubMed).
: "Transgenic mice demonstrate that epithelial homing of gamma/delta T cells is determined by cell lineages independent of T cell receptor specificity." in: The Journal of experimental medicine, Vol. 171, Issue 4, pp. 1015-26, (1990) (PubMed).
: "Transport and secretion of truncated T cell receptor beta-chain occurs in the absence of association with CD3." in: The Journal of biological chemistry, Vol. 265, Issue 16, pp. 9296-301, (1990) (PubMed).
: "Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 8, pp. 2736-42, (1989) (PubMed).
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: "Different initiation of pre-TCR and gammadeltaTCR signalling." in: Nature, Vol. 406, Issue 6795, pp. 524-7, (2000) (PubMed).
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- 抗原
- TCR beta (T Cell Receptor (TCR) beta (TCR beta))
- Abstract
- TCR beta 产品
- 别名
- TCRbeta antibody, Tib antibody, T cell receptor beta chain antibody, Tcrb antibody
- 背景
- The H57-597 antibody reacts with a common epitope of the beta chain of the T-cell Receptor (TCR) complex on alphabeta TCR-expressing thymocytes and peripheral T lymphocytes and NK1.1+ thymocytes and NK-T cells of all mouse strains tested. It does not react with gammadelta TCR-bearing T cells. In the fetal and adult thymus, the TCR beta-chain may form homodimers or pair with the pre-TCR alpha-chain on the surface of immature thymocytes before expression of the TCR alpha-chain. Plate-bound or soluble H57-597 antibody activates alphabeta TCR-bearing T cells, and plate-bound mAb can induce apoptotic death.
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