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- 抗原 See all HLA-ABC 抗体
- HLA-ABC
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-ABC antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Blocking Reagent (BR)
- 品牌
- BD Pharmingen™
- 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- 免疫原
- Polyclonal Human NK Cell Line
- 克隆位点
- DX17
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product HLA-ABC Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor." in: The Journal of experimental medicine, Vol. 181, Issue 3, pp. 1133-44, (1995) (PubMed).
: "The NKB1 and HP-3E4 NK cells receptors are structurally distinct glycoproteins and independently recognize polymorphic HLA-B and HLA-C molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 7, pp. 3320-7, (1995) (PubMed).
: "Orientation of loci within the human major histocompatibility complex by chromosomal in situ hybridization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 81, Issue 9, pp. 2816-20, (1984) (PubMed).
: "Hu-1: Major histocompatibility locus in man." in: Science (New York, N.Y.), Vol. 156, Issue 3781, pp. 1506-8 (PubMed).
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The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor." in: The Journal of experimental medicine, Vol. 181, Issue 3, pp. 1133-44, (1995) (PubMed).
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- 抗原
- HLA-ABC
- 别名
- HLA-A/B/C (HLA-ABC 产品)
- 别名
- HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
- 背景
- The DX17 monoclonal antibody reacts with a monomorphic epitope expressed on all HLA (human leukocyte antigen) class I molecules examined. DX17 immunoprecipitates HLA class I heavy chains (45 kDa) and beta2-microglobulin (12kDa) from radiolabeled human cell lines. HLA is determined by a complex segment of the short arm of chromosome 6 and there are many human HLAs encoded in this segment. The antigenic agglomerate is called MHC, for major histocompatibility complex. Examples of class I loci are HLA-A, -B, and -C, which are serologically assayed, class II loci, e.g., HLA-D/DR and DC1, are tested by lymphocytotoxic methods.
- 途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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