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- 抗原 See all WIPF1 抗体
- WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))
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抗原表位
- pSer488
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This WIPF1 antibody is conjugated to PE
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应用范围
- Intracellular Staining (ICS)
- 品牌
- BD Phosflow™
- 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Phosphorylated Human WIP Peptide
- 克隆位点
- K32-824
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product WIPF1 Primary Antibody
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- 样本量
- 20 μL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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The verprolin family of proteins: regulators of cell morphogenesis and endocytosis." in: FEBS letters, Vol. 579, Issue 24, pp. 5253-9, (2005) (PubMed).
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The verprolin family of proteins: regulators of cell morphogenesis and endocytosis." in: FEBS letters, Vol. 579, Issue 24, pp. 5253-9, (2005) (PubMed).
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- 抗原
- WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))
- 别名
- WIP (WIPF1 产品)
- 别名
- WASPIP antibody, PRPL-2 antibody, WIP antibody, AI115543 antibody, D2Ertd120e antibody, Waspip antibody, Wip antibody, WAS/WASL interacting protein family member 1 antibody, WAS/WASL interacting protein family, member 1 antibody, WIPF1 antibody, Wipf1 antibody
- 背景
- Wiskott-Adrich syndrome protein (WASP)-Interacting Protein (WIP) is a member of the verprolin family of proteins that regulate cytoskeletal organization in a wide variety of cellular activities, including endocytosis, cellular adhesion and migration, mast cell degranulation, and lymphocyte activation. The 503-amino acid WIP protein contains binding sites for actin (globular and filamentous) and other proteins that are involved in the regulation of actin polymerization, such as WASP, N-WASP, profilin, cortactin, Hck, and NCK. As its functions imply, WIP is localized in actin-rich cell structures. The K32-824 monoclonal antibody recognizes the phosphorylated serine 488 (pS488) of human WIP. The orthologous phosphorylation sites in mouse and rat WIP are S478 and S472, respectively.
- 途径
- RTK signaling
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