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IL3RA 抗体 (PE)

Name: IL3RA 抗体 (PE)
Brand: antibodies-online
SKU: ABIN1176839
Availability: OutOfStock

IL3RA 适用: 人 FACS 宿主: 小鼠 Monoclonal 6H6 PE

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD123 (6H6) PE antibody (10 μL reagent / 100 μL of peripheral whole blood). (IL3RA 抗体 (PE))

FACS

Surface staining of human peripheral blood with anti-CD123 (6H6) PE. (IL3RA 抗体 (PE))

FACS

Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human CD123 (6H6) PE antibody (10 μL reagent / 100 μL of peripheral whole blood) and anti-human CD45 (MEM-28) Pacific Blue antibody (10 μL reagent / 100 μL of peripheral whole blood). (IL3RA 抗体 (PE))

FACS

Separation of human CD123 positive Basophil granulocytes(red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD123 (6H6) PE antibody (10 μL reagent / 100 μL of peripheral whole blood). (IL3RA 抗体 (PE))

FACS

4 images

(3 references)

产品编号 ABIN1176839

发货至: 中国

Datasheet as PDF

抗原 See all IL3RA 抗体

IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
适用
106

32

3
人
宿主
58

51

3

1
小鼠
Compatible Secondaries
克隆类型
64

48

1
单克隆
标记
46

8

8

7

6

5

5

4

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This IL3RA antibody is conjugated to PE
应用范围
71

55

15

15

13

13

11

9

8

4

4

3

2

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS)

特异性

The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.

交叉反应（详细）

Human

纯化方法

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells

克隆位点

6H6

亚型

IgG1

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anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 19-158) antibody
IL3RA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 201-300) antibody
IL3RA 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 167-331) antibody
IL3RA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 26-171) antibody
IL3RA 适用: 人 IHC, ELISA, ISt, StM, Coat 宿主: 兔 Monoclonal IL3RA-2947R unconjugated Recombinant Antibody

anti-Interleukin 3 Receptor, alpha (IL3RA) antibody
IL3RA 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 3 Receptor, alpha (IL3RA) antibody
IL3RA 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 6H6 unconjugated

anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 19-305) antibody
IL3RA 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM31 unconjugated

anti-Interleukin 3 Receptor, alpha (IL3RA) antibody (Biotin)
IL3RA 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 6H6 Biotin

应用备注

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

说明

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

限制

仅限研究用
溶解方式

No reconstitution is necessary.

缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.
Avoid prolonged exposure to light.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Martín-Gayo, Sierra-Filardi, Corbí, Toribio: "Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development." in: Blood, Vol. 115, Issue 26, pp. 5366-75, (2010) (PubMed).

Herling, Teitell, Shen, Medeiros, Jones: "TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin." in: Blood, Vol. 101, Issue 12, pp. 5007-9, (2003) (PubMed).

Sun, Woodcock, Rapoport, Stomski, Korpelainen, Bagley, Goodall, Smith, Gamble, Vadas, Lopez: "Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist." in: Blood, Vol. 87, Issue 1, pp. 83-92, (1996) (PubMed).
抗原

IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

别名

CD123 (IL3RA 产品)

别名

CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody

背景

Interleukin 3 receptor subunit alpha,CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.,IL3RA, MGC34174, hIL-3Ra

基因ID

3563

UniProt

P26951

途径

JAK/STAT Signaling