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- 抗原 See all NOD1 抗体
- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
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抗原表位
- AA 2-31
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Recognizes human Nod1.
- 交叉反应
- 人
- 免疫原
- Synthetic peptide corresponding to aa 2-31 (E2EQGHSEMEIIPSESHPHIQLLKSNRELLV31) of human Nod1.
- Top Product
- Discover our top product NOD1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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NOD protein expression and function in first trimester trophoblast cells." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 57, Issue 1, pp. 67-80, (2006) (PubMed).
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NOD protein expression and function in first trimester trophoblast cells." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 57, Issue 1, pp. 67-80, (2006) (PubMed).
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- 抗原
- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
- 别名
- Nod1 (NOD1 产品)
- 别名
- CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, C230079P11 antibody, Card4 antibody, F830007N14Rik antibody, Nlrc1 antibody, RGD1562269 antibody, nucleotide binding oligomerization domain containing 1 antibody, nucleotide-binding oligomerization domain containing 1 antibody, NOD1 antibody, Nod1 antibody
- 背景
- Nod (CARD4) is a cytosolic pattern recognition molecule (PRRs) of the NLR (NOD-like receptor) family. Nod1 is widely expressed by many cell types and is implicated in sensing meso-diaminopimelic acid (meso-DAP)-containing PGN fragments, which are present in most Gramnegative bacteria and certain Gram-positive ones, like the Bacillus species. Upon activation, Nod1 initiates a pro-inflammatory response through NF-kappa signaling and is a key receptors in epithelial cells where it controls infections via the gastrointestinal system. Mutations in Nod1 have been reported to confer susceptibility to several inflammatory disorders including inflammatory bowel disease, atopic eczema and asthma.
- UniProt
- Q8BHB0
- 途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
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