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- 抗原 See all ANGPTL4 抗体
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ANGPTL4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- Recognizes the fibrinogen-like domain (FLD) of human ANGPTL4. Detects a band of ~62 kDa and ~35 kDa by Western blot.
- 交叉反应
- 人
- 交叉反应 （详细）
- Does not cross-react with other ANGPTL family proteins.
- 过滤
- 0.2 μm filtered
- 免疫原
- Recombinant human ANGPTL4.
- 克隆位点
- Kairos-1
- 亚型
- IgG1
- Top Product
- Discover our top product ANGPTL4 Primary Antibody
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anti-Angiopoietin-Like 4 (ANGPTL4) (AA 182-388) antibody
ANGPTL4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) (AA 182-394) antibodyANGPTL4 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) (AA 1-406) antibodyANGPTL4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) (AA 26-406) antibodyANGPTL4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) (AA 138-167) antibodyANGPTL4 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) (AA 26-406) antibodyANGPTL4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) (AA 1-406) antibodyANGPTL4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) (AA 138-167) antibodyANGPTL4 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18264 unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) (AA 26-406) antibodyANGPTL4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Angiopoietin-Like 4 (ANGPTL4) antibodyANGPTL4 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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- 抗原
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
- 别名
- ANGPTL4 (ANGPTL4 产品)
- 别名
- ANGPTL2 antibody, ARP4 antibody, FIAF antibody, HFARP antibody, NL2 antibody, PGAR antibody, pp1158 antibody, Arp4 antibody, Bk89 antibody, Fiaf antibody, Hfarp antibody, Ng27 antibody, Pgar antibody, Pgarg antibody, Pp1158 antibody, ANGPTL4 antibody, fiaf antibody, im:7144703 antibody, si:rp71-39b20.7 antibody, angiopoietin like 4 antibody, angiopoietin-like 4 antibody, ANGPTL4 antibody, Angptl4 antibody, angptl4 antibody
- 背景
- ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.
- UniProt
- Q9BY76
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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