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- 抗原 See all MEFV 抗体
- MEFV (Mediterranean Fever (MEFV))
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抗原表位
- AA 2-29
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MEFV antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 特异性
- Recognizes human pyrin.
- 交叉反应
- 人
- 免疫原
- Synthetic peptide corresponding to aa 2-29 (A2KTPSDHLLSTLEELVPYDFEKFKFKLQ29) of human pyrin.
- Top Product
- Discover our top product MEFV Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." in: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, (2007) (PubMed).
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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." in: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, (2007) (PubMed).
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- 抗原
- MEFV (Mediterranean Fever (MEFV))
- 别名
- Pyrin (MEFV 产品)
- 别名
- pyrin antibody, MEFV antibody, FMF antibody, MEF antibody, TRIM20 antibody, rfp domain antibody, MEFV, pyrin innate immunity regulator antibody, Mediterranean fever antibody, MEFV antibody, Mefv antibody
- 背景
- Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.
- UniProt
- O15553
- 途径
- Positive Regulation of Endopeptidase Activity
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