TNFSF9 抗体 (Extracellular Domain)
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- 抗原 See all TNFSF9 抗体
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
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抗原表位
- Extracellular Domain
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFSF9 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 特异性
- Recognizes extracellular domain of human CD137L.
- 交叉反应
- 人
- 无交叉反应
- 小鼠
- 交叉反应 (详细)
- Does not cross-react with mouse CD137L.
- 过滤
- 0.2 μm filtered
- 免疫原
- Recombinant human CD137L extracellular domain.
- 克隆位点
- 41B436
- 亚型
- IgG1
- Top Product
- Discover our top product TNFSF9 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling." in: PLoS ONE, Vol. 5, Issue 5, pp. e10845, (2010) (PubMed).
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Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling." in: PLoS ONE, Vol. 5, Issue 5, pp. e10845, (2010) (PubMed).
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- 抗原
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- 别名
- CD137L (TNFSF9 产品)
- 别名
- TNFSF9 antibody, 4-1BB-L antibody, 4-1BBL antibody, AI848817 antibody, Cd137l antibody, Ly63l antibody, CD137L antibody, TNF superfamily member 9 antibody, tumor necrosis factor (ligand) superfamily, member 9 antibody, Tnfsf9 antibody, LOC476729 antibody, TNFSF9 antibody
- 背景
- The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
- UniProt
- P41273
- 途径
- Activated T Cell Proliferation, Cancer Immune Checkpoints
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