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- 抗原 See all ARHGEF7 抗体
- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGEF7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 特异性
- Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms.
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 (详细)
- Cross-reacts with human and rat beta-Pix.
- 过滤
- 0.2 μm filtered
- 免疫原
- Recombinant beta-Pix SH3 domain.
- Top Product
- Discover our top product ARHGEF7 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).
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Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).
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- 抗原
- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
- 别名
- beta-Pix (ARHGEF7 产品)
- 别名
- BETA-PIX antibody, COOL-1 antibody, COOL1 antibody, Nbla10314 antibody, P50 antibody, P50BP antibody, P85 antibody, P85COOL1 antibody, P85SPR antibody, PAK3 antibody, PIXB antibody, cool1 antibody, p50 antibody, p85 antibody, pak3 antibody, pixb antibody, ARHGEF7 antibody, P85spr antibody, Pak3bp antibody, Cool antibody, PIX antibody, betaPix antibody, betaPix-b antibody, betaPix-c antibody, cool-1 antibody, mKIAA0142 antibody, p85Cool1 antibody, p85SPR antibody, arhgef7 antibody, bbh antibody, bpix antibody, im:7142367 antibody, wu:fc35h08 antibody, zgc:101775 antibody, Rho guanine nucleotide exchange factor 7 antibody, Rho guanine nucleotide exchange factor 7 S homeolog antibody, ankyrin repeat domain 10 antibody, Rho guanine nucleotide exchange factor (GEF7) antibody, Rho guanine nucleotide exchange factor (GEF) 7b antibody, ARHGEF7 antibody, arhgef7.S antibody, arhgef7 antibody, ANKRD10 antibody, Arhgef7 antibody, arhgef7b antibody
- 背景
- Beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
- UniProt
- Q9ES28
- 途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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