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ARHGEF7 抗体

ARHGEF7 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1169227
发货至: 中国
  • 抗原 See all ARHGEF7 抗体
    ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
    适用
    人, 大鼠, 小鼠
    宿主
    • 45
    • 2
    克隆类型
    • 46
    • 1
    多克隆
    标记
    • 18
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF7 antibody is un-conjugated
    应用范围
    • 22
    • 21
    • 13
    • 13
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    特异性
    Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms.
    交叉反应
    人, 小鼠, 大鼠
    交叉反应 (详细)
    Cross-reacts with human and rat beta-Pix.
    过滤
    0.2 μm filtered
    免疫原
    Recombinant beta-Pix SH3 domain.
    Top Product
    Discover our top product ARHGEF7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • Oh, Yoo, Jo, Song, Kim, Park: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).

  • 抗原
    ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
    别名
    beta-Pix (ARHGEF7 产品)
    背景
    Beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
    UniProt
    Q9ES28
    途径
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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