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- 抗原 See all ARHGEF7 抗体
- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGEF7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 特异性
- Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms.
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 (详细)
- Cross-reacts with human and rat beta-Pix.
- 过滤
- 0.2 μm filtered
- 免疫原
- Recombinant beta-Pix SH3 domain.
- Top Product
- Discover our top product ARHGEF7 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).
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Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).
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- 抗原
- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
- 别名
- beta-Pix (ARHGEF7 产品)
- 背景
- Beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
- UniProt
- Q9ES28
- 途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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