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- 抗原 See all TICAM2 抗体
- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
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抗原表位
- AA 2-29
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TICAM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Recognizes human TRAM.
- 交叉反应
- 人
- 免疫原
- Synthetic peptide corresponding to aa 2-29 (G2IGKSKINSCPLSLSWGKRHSVDTSPGY29) of human TRAM.
- Top Product
- Discover our top product TICAM2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Neat serum containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." in: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).
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Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." in: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).
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- 抗原
- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
- 别名
- TRAM (TICAM2 产品)
- 别名
- MyD88-4 antibody, TICAM-2 antibody, TIRAP3 antibody, TIRP antibody, TRAM antibody, B430113A10 antibody, Tirp antibody, Trif antibody, toll like receptor adaptor molecule 2 antibody, toll-like receptor adaptor molecule 2 antibody, TICAM2 antibody, Ticam2 antibody
- 背景
- TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas.
- UniProt
- Q86XR7
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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