DLK1 抗体 (Extracellular Domain)
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Quick Overview for DLK1 抗体 (Extracellular Domain) (ABIN1169188)
抗原
See all DLK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Extracellular Domain
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原理
- anti-DLK1 (human), pAb
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特异性
- Recognizes human DLK1. Detects a band of ~42 kDa by Western blot.
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产品特性
- Polyclonal Antibody. Recognizes human DLK1. Detects a band of ~42 kDa by Western blot. Source: Rat. Applications: ELISA, FACS, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human DLK1 (extracellular domain).
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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有效期
- 6 months
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- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
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别名
- DLK1
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背景
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Alternate Names/Synonyms: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
Product Description: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
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UniProt
- P80370
抗原
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