IL23A 抗体
Our Local Distributor
北京 101111
Quick Overview for IL23A 抗体 (ABIN1169135)
抗原
See all IL23A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- anti-IL-23p19 (human), mAb (I 178G)
-
特异性
- Recognizes human IL-23p19.
-
产品特性
- Monoclonal Antibody. Recognizes human IL-23p19. Isotype: Rat IgG2akappa. Clone: I 178G. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
-
过滤
- 0.2 μm filtered
-
免疫原
- Recombinant human IL-23p19.
-
亚型
- IgG2a kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
-
储存液
- Without preservative
-
注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
-
有效期
- 12 months
-
-
- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
-
别名
- IL-23p19
-
背景
-
Alternate Names/Synonyms: Interleukin-23 Subunit p19, Interleukin-23 Subunit alpha, IL-23-A
Product Description: IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
-
UniProt
- Q9NPF7
-
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
-