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LAG3 抗体
LAG3
适用: 人, 猴
WB, ELISA, IHC, ICC, IP, Func
宿主: 小鼠
Monoclonal
1-10E-04
unconjugated
LAG3抗体详情
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抗原
See all LAG3 抗体
LAG3
(Lymphocyte-Activation Gene 3 (LAG3))
适用
All reactivities for LAG3 抗体
人, 猴
宿主
All hosts for LAG3 抗体
小鼠
克隆类型
All clonalities for LAG3 抗体
单克隆
标记
All conjugates for LAG3 抗体
This LAG3 antibody is un-conjugated
应用范围
All applications for LAG3 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Functional Studies (Func)
特异性
Recognizes human and monkey LAG-3.
交叉反应
人, 猴
纯化方法
Purified from concentrated hybridoma tissue culture supernatant.
纯度
>95 % (SDS-PAGE)
内毒素水平
<0.001EU/μg purified protein or <1EU/mg purified protein (LAL test, Lonza).
免疫原
Recombinant human LAG-3.
克隆位点
1-10E-04
亚型
IgG1
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
Lot specific
缓冲液
In PBS.
储存液
Without preservative
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
有效期
12 months
LAG3目标详情
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抗原
LAG3
(Lymphocyte-Activation Gene 3 (LAG3))
别名
LAG-3 (LAG3 产品 )
别名
CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
背景
Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
UniProt
P18627
途径
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cancer Immune Checkpoints
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