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NOTCH2 抗体

NOTCH2 适用: 人, 小鼠 FACS 宿主: 大鼠 Monoclonal 16F11 unconjugated
产品编号 ABIN1169006
发货至: 中国
  • 抗原 See all NOTCH2 抗体
    NOTCH2 (Notch 2 (NOTCH2))
    适用
    • 67
    • 49
    • 30
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 75
    • 5
    • 2
    • 1
    • 1
    大鼠
    克隆类型
    • 74
    • 7
    • 2
    单克隆
    标记
    • 40
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    • 3
    • 2
    • 2
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    • 2
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH2 antibody is un-conjugated
    应用范围
    • 48
    • 32
    • 26
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    • 18
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    • 11
    • 11
    • 7
    • 6
    • 3
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    Flow Cytometry (FACS)
    特异性
    Recognizes human and mouse endogenous Notch-2 receptor.
    交叉反应
    人, 小鼠
    纯化方法
    Purified from concentrated hybridoma tissue culture supernatant.
    纯度
    >95 % (SDS-PAGE)
    免疫原
    Recombinant mouse Notch2:Fc .
    克隆位点
    16F11
    亚型
    IgG1
    Top Product
    Discover our top product NOTCH2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • Ribeiro, Hasan, Wilson, Boucontet, Pereira, Lesjean-Pottier, Satoh-Takayama, Di Santo, Vosshenrich: "Cutting edge: Thymic NK cells develop independently from T cell precursors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 9, pp. 4993-7, (2010) (PubMed).

    Fiorini, Merck, Wilson, Ferrero, Jiang, Koch, Auderset, Laurenti, Tacchini-Cottier, Pierres, Radtke, Luther, Macdonald: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).

  • 抗原
    NOTCH2 (Notch 2 (NOTCH2))
    别名
    Notch2 (NOTCH2 产品)
    别名
    AGS2 antibody, HJCYS antibody, hN2 antibody, AI853703 antibody, N2 antibody, notch6 antibody, sb:cb884 antibody, neurogenic locus notch homolog protein 2 antibody, notch 2 antibody, notch 3 antibody, LOC581186 antibody, NOTCH2 antibody, notch3 antibody, Notch2 antibody, notch2 antibody
    背景
    Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
    UniProt
    O35516
    途径
    Notch Signaling, Stem Cell Maintenance
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