LYVE1 抗体 (AA 24-226)
(19 references)-
- 抗原 See all LYVE1 抗体
- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
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抗原表位
- AA 24-226
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LYVE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody detetcs Lyve-1.
- 交叉反应 （详细）
- Species reactivity (tested):Mouse. This antibody is not reactive with Human LYVE-1.
- 纯化方法
- Protein G Chromatography (+ his tag depletetion)
- 免疫原
- Highly pure recombinant Mouse soluble LYVE-1 produced in insect cells. This recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis).
- Top Product
- Discover our top product LYVE1 Primary Antibody
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anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 231-318) antibody
LYVE1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 46-77), (N-Term) antibodyLYVE1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2930 unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 20-238) antibodyLYVE1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 24-228) antibodyLYVE1 适用: 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 20-238) antibodyLYVE1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) antibodyLYVE1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) antibodyLYVE1 适用: 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (N-Term) antibodyLYVE1 适用: 人, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 24-228) antibodyLYVE1 适用: 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA (1-15 μg/mL). Western blot (1-2 μg/mL). FACS analysis (3-20 μg/mL). Immunohistochemistry on Frozen Sections (1-5 μg/mL). For formalin-fixed, paraffin-embedded sections use the immunogen affinity purifiedantibody ABIN115689.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore in sterile water/PBS to a concentration of > 0.5 mg/mL.
- 缓冲液
- PBS, pH 7.2 without preservatives or stabilizers
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The lyophilized IgG is stable at 2-8 °C for one month and at -20 °C for longer. When reconstituted the antibody is stable for at least six weeks at 2-8 °C. For longer store in aliquots at -20 °C.
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: "Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function." in: Radiation research, Vol. 184, Issue 4, pp. 352-66, (2015) (PubMed).
: "The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its length." in: Biological chemistry, Vol. 395, Issue 10, pp. 1201-19, (2015) (PubMed).
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: "Anti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 2, pp. 382-98, (2015) (PubMed).
: "Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats." in: Neurobiology of aging, Vol. 36, Issue 2, pp. 1194-208, (2015) (PubMed).
: "Short-chain fatty acids and acidic pH upregulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 308, Issue 4, pp. R283-93, (2015) (PubMed).
: "SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma." in: Virchows Archiv : an international journal of pathology, Vol. 465, Issue 6, pp. 649-59, (2015) (PubMed).
: "Cytosolic dynamics of annexin A6 trigger feedback regulation of hypertrophy via atrial natriuretic peptide in cardiomyocytes." in: The Journal of biological chemistry, Vol. 289, Issue 9, pp. 5371-85, (2014) (PubMed).
: "Expression and localization of a UT-B urea transporter in the human bladder." in: American journal of physiology. Renal physiology, Vol. 307, Issue 9, pp. F1088-94, (2014) (PubMed).
: "Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 6, pp. 1585-97, (2014) (PubMed).
: "Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer." in: British journal of cancer, Vol. 108, Issue 11, pp. 2321-8, (2013) (PubMed).
: "Autism-specific maternal autoantibodies recognize critical proteins in developing brain." in: Translational psychiatry, Vol. 3, pp. e277, (2013) (PubMed).
: "Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7." in: Molecular cancer research : MCR, Vol. 10, Issue 6, pp. 713-26, (2012) (PubMed).
: "Roles of heparan sulfate sulfation in dentinogenesis." in: The Journal of biological chemistry, Vol. 287, Issue 15, pp. 12217-29, (2012) (PubMed).
: "Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1950-8, (2010) (PubMed).
: "Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo." in: Circulation, Vol. 119, Issue 2, pp. 281-9, (2009) (PubMed).
: "Pax6 is essential for lens fiber cell differentiation." in: Development (Cambridge, England), Vol. 136, Issue 15, pp. 2567-78, (2009) (PubMed).
: "Dendritic cell-nerve clusters are sites of T cell proliferation in allergic airway inflammation." in: The American journal of pathology, Vol. 174, Issue 3, pp. 808-17, (2009) (PubMed).
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: "Up-regulation of TREK-2 potassium channels in cultured astrocytes requires de novo protein synthesis: relevance to localization of TREK-2 channels in astrocytes after transient cerebral ischemia." in: PLoS ONE, Vol. 10, Issue 4, pp. e0125195, (2016) (PubMed).
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- 抗原
- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
- 别名
- LYVE-1 (LYVE1 产品)
- 别名
- LYVE1 antibody, XLKD1 antibody, CRSBP-1 antibody, HAR antibody, LYVE-1 antibody, 1200012G08Rik antibody, Crsbp-1 antibody, Lyve-1 antibody, Xlkd1 antibody, lymphatic vessel endothelial hyaluronic receptor 1a antibody, lymphatic vessel endothelial hyaluronan receptor 1 antibody, lyve1a antibody, LYVE1 antibody, Lyve1 antibody
- 背景
- LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212- esidue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE- molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymphspecific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1
- 基因ID
- 114332
- NCBI登录号
- NP_444477
- UniProt
- Q8BHC0
- 途径
- Glycosaminoglycan Metabolic Process
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