Chromogranin A 抗体 (C-Term)
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- 抗原 See all Chromogranin A (CHGA) 抗体
- Chromogranin A (CHGA)
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Chromogranin A antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
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This antibody reacts with human Chromogranin A in the neuroendocrine cells and neural tissues. It does not recognizes the epitopes located on the N-terminal half of the chromogranin A molecule.
Cellular Localization: Cytoplasmic. - 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Purified
- 免疫原
- C-terminal half of chromogranin A was purified from urine of patients with carcinoid syndrome.
- Top Product
- Discover our top product CHGA Primary Antibody
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- 应用备注
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Immunohistochemistry on Paraffin Embedded Sections: 1/20-1/50 in an ABC method(30-60 minutes at room temperature)Recommended Positive Control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM Citrate buffer, pH 6.0 containing Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Chromogranin A (CHGA)
- 别名
- Chromogranin A (CHGA 产品)
- 背景
- Chromogranin A (a protein of 439 amino acids which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.Synonyms: CHGA, CgA, Chromogranin-A, Pituitary secretory protein I, SP-I
- 基因ID
- 1113
- NCBI登录号
- NP_001266
- UniProt
- P10645
- 途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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