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MAP2 抗体

MAP2 适用: Cow WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN112902
发货至: 中国
  • 抗原 See all MAP2 抗体
    MAP2 (Microtubule-Associated Protein 2 (MAP2))
    适用
    • 134
    • 83
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    • 24
    • 5
    • 5
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    • 1
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    Cow
    宿主
    • 107
    • 40
    • 9
    • 2
    克隆类型
    • 119
    • 38
    多克隆
    标记
    • 79
    • 14
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    • 4
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    • 3
    • 3
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    • 1
    This MAP2 antibody is un-conjugated
    应用范围
    • 114
    • 57
    • 50
    • 39
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    • 30
    • 26
    • 21
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    • 19
    • 15
    • 9
    • 4
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    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Prepared by Ammonium Sulphate fractionation
    免疫原
    Native, from brain
    Top Product
    Discover our top product MAP2 Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections (1: 5 - 1: 30). Western blot (Recognises mainly the MAP2 protein (280 kD) and to a lesser extent the Tauprotein (60 kD) in blotting using bovine brain extract. When testing against rat brainextract this antibody shows strong bands at 60 kD and fainter bands at the highermolecular weights. This could be due to differences in the sample preparation).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    25.5 mg/mL
    缓冲液
    PBS, pH 7.2, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MAP2 (Microtubule-Associated Protein 2 (MAP2))
    Abstract
    MAP2 产品
    别名
    MAP2A antibody, MAP2B antibody, MAP2C antibody, MAP2R antibody, Mtap2 antibody, MAP-2 antibody, Mtap-2 antibody, xmap2 antibody, MGC53131 antibody, a730034c02 antibody, zgc:103474 antibody, zgc:113974 antibody, microtubule associated protein 2 antibody, microtubule-associated protein 2 antibody, microtubule associated protein 2 S homeolog antibody, MAP2 antibody, Map2 antibody, map2.S antibody, map2 antibody
    背景
    MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2, two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
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