CD49c / CD49f (Isoform B), (N-Term) 抗体
适用: 人
IHC (fro), IF, WB
宿主: 小鼠
Monoclonal
PB36
unconjugated
-
- 抗原
- CD49c / CD49f
- 抗原表位
- Isoform B, N-Term
- 适用
- 人
- 宿主
- 小鼠
- 克隆类型
- 单克隆
- 应用范围
- Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
- 交叉反应 （详细）
-
Species reactivity (expected):A broad species reactivity is expected because of the conserved nature of the epitope.
Species reactivity (tested):Human. - 纯化方法
- Purified
- 免疫原
- PB36 is a mouse monoclonal IgG1, k antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a synthetic peptide corresponding to a 32 amino acid stretch in the cytoplasmic domain of integrin a3B including an appending N-terminal cysteine (CTRYYQIMPKYHAVRIREEERYPPPGSTLPTKK) coupled to keyhole limpet hemocyanin.
- 克隆位点
- PB36
- 亚型
- IgG1
-
- 应用备注
-
Suitable for Immunoblotting, Immunocytochemistry, Immunohistochemistry on frozentissues. Recommended dilutions: 1/50-1/100 for Immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent, and 1/100-1/500 forImmunoblotting applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS with 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store lyophilized at 2-8 °C. After reconstitution aliquot and store at -20 °C.
-
- 抗原
- CD49c / CD49f
- 背景
- Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated a and b subunits. More than 18 a and 8 b subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits a3 and a6, two cytoplasmic variants, A and B, have been identified.Synonyms: Integrin alpha 3B / Integrin alpha 6B
-
You are here:
