CD68 抗体 (FITC)
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- 抗原 See all CD68 抗体
- CD68 (CD68 Molecule (CD68))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD68 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- CD68 antibody BM4111F recognizes the 110KD integral membrane glycoprotein CD68 (Macrosialin) predominantly expressed on the intracellular lysosomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes.
- 产品特性
- Absorption / Emission: 495 nm / 528 nm
- 纯化方法
- Protein A Chromatography
- 免疫原
- Cell suspensions of Human lymph node
- 克隆位点
- Ki-M7
- 亚型
- IgG1
- Top Product
- Discover our top product CD68 Primary Antibody
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- 应用备注
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Flow Cytometry: Use 10 μL to label 10^6 cells in 100 μL (Membrane permeabilisation isrequired). Clone KiM7 has been reported as being also suitable for use in Immunoprecipitation andImmunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS, 0.05 % Sodium Azide, 1 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- CD68 (CD68 Molecule (CD68))
- 别名
- CD68 (CD68 产品)
- 背景
- The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukaemia studies.Synonyms: Gp110, Macrophage marker, Macrosialin
- 基因ID
- 968
- NCBI登录号
- NP_001035148
- UniProt
- P34810
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