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- 抗原 See all CD27 抗体
- CD27 (CD27 Molecule (CD27))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD27 antibody is conjugated to PE-DyLight 594
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody LT27 reacts with an extracellular epitope of CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-DyLight®594 (PE-DyLight®594) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Human peripheral blood lymphocytes
- 克隆位点
- LT27
- 亚型
- IgG2a
- Top Product
- Discover our top product CD27 Primary Antibody
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anti-CD27 Molecule (CD27) (AA 1-260) antibody
CD27 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1E2-A3 unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 适用: 人 FACS, ELISA, IHC, IF, StM, Coat 宿主: 小鼠 Monoclonal LPFS2-1611 unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 20-191) antibodyCD27 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 20-144) antibodyCD27 适用: 人 FACS, WB, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 3B6D3 unconjugated
anti-CD27 Molecule (CD27) (AA 196-225) antibodyCD27 适用: 人 FACS, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 229-312) antibodyCD27 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 适用: 人 FACS, IHC, StM 宿主: 小鼠 Monoclonal rLPFS2-1611 unconjugated Recombinant Antibody
anti-CD27 Molecule (CD27) antibodyCD27 适用: 人 FACS 宿主: 小鼠 Monoclonal LT27 unconjugated
anti-CD27 Molecule (CD27) (AA 20-191) antibodyCD27 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM57 unconjugated Recombinant Antibody
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with tandem dye PE-DyLight™, 594 (PE-DL594) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 溶解方式
- No reconstitution is necessary.
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze.
Avoid prolonged exposure to light. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- CD27 (CD27 Molecule (CD27))
- 别名
- CD27 (CD27 产品)
- 别名
- TNFRSF7 antibody, S152 antibody, Tnfrsf7 antibody, Tp55 antibody, S152. LPFS2 antibody, T14 antibody, CD27 molecule antibody, CD27 antigen antibody, CD27 antibody, Cd27 antibody
- 背景
- CD27 Molecule,CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.,T14, TNFRSF7, LPFS2, S152, Tp55
- 基因ID
- 939
- UniProt
- P26842
- 途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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